Cargando…

The accuracy of Acuros XB algorithm for radiation beams traversing a metallic hip implant — comparison with measurements and Monte Carlo calculations

In this study, the clinical benefit of the improved accuracy of the Acuros XB (AXB) algorithm, implemented in a commercial radiotherapy treatment planning system (TPS), Varian Eclipse, was demonstrated with beams traversing a high‐Z material. This is also the first study assessing the accuracy of th...

Descripción completa

Detalles Bibliográficos
Autores principales: Ojala, Jarkko, Kapanen, Mika, Sipilä, Petri, Hyödynmaa, Simo, Pitkänen, Maunu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711096/
https://www.ncbi.nlm.nih.gov/pubmed/25207577
http://dx.doi.org/10.1120/jacmp.v15i5.4912
_version_ 1783283006992023552
author Ojala, Jarkko
Kapanen, Mika
Sipilä, Petri
Hyödynmaa, Simo
Pitkänen, Maunu
author_facet Ojala, Jarkko
Kapanen, Mika
Sipilä, Petri
Hyödynmaa, Simo
Pitkänen, Maunu
author_sort Ojala, Jarkko
collection PubMed
description In this study, the clinical benefit of the improved accuracy of the Acuros XB (AXB) algorithm, implemented in a commercial radiotherapy treatment planning system (TPS), Varian Eclipse, was demonstrated with beams traversing a high‐Z material. This is also the first study assessing the accuracy of the AXB algorithm applying volumetric modulated arc therapy (VMAT) technique compared to full Monte Carlo (MC) simulations. In the first phase the AXB algorithm was benchmarked against point dosimetry, film dosimetry, and full MC calculation in a water‐filled anthropometric phantom with a unilateral hip implant. Also the validity of the full MC calculation used as reference method was demonstrated. The dose calculations were performed both in original computed tomography (CT) dataset, which included artifacts, and in corrected CT dataset, where constant Hounsfield unit (HU) value assignment for all the materials was made. In the second phase, a clinical treatment plan was prepared for a prostate cancer patient with a unilateral hip implant. The plan applied a hybrid VMAT technique that included partial arcs that avoided passing through the implant and static beams traversing the implant. Ultimately, the AXB‐calculated dose distribution was compared to the recalculation by the full MC simulation to assess the accuracy of the AXB algorithm in clinical setting. A recalculation with the anisotropic analytical algorithm (AAA) was also performed to quantify the benefit of the improved dose calculation accuracy of type ‘c’ algorithm (AXB) over type ‘b’ algorithm (AAA). The agreement between the AXB algorithm and the full MC model was very good inside and in the vicinity of the implant and elsewhere, which verifies the accuracy of the AXB algorithm for patient plans with beams traversing through high‐Z material, whereas the AAA produced larger discrepancies. PACS numbers: 87.55.‐x, 87.55.D‐, 87.55.K‐, 87.55.kd, 87.55.Qr
format Online
Article
Text
id pubmed-5711096
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-57110962018-04-02 The accuracy of Acuros XB algorithm for radiation beams traversing a metallic hip implant — comparison with measurements and Monte Carlo calculations Ojala, Jarkko Kapanen, Mika Sipilä, Petri Hyödynmaa, Simo Pitkänen, Maunu J Appl Clin Med Phys Radiation Oncology Physics In this study, the clinical benefit of the improved accuracy of the Acuros XB (AXB) algorithm, implemented in a commercial radiotherapy treatment planning system (TPS), Varian Eclipse, was demonstrated with beams traversing a high‐Z material. This is also the first study assessing the accuracy of the AXB algorithm applying volumetric modulated arc therapy (VMAT) technique compared to full Monte Carlo (MC) simulations. In the first phase the AXB algorithm was benchmarked against point dosimetry, film dosimetry, and full MC calculation in a water‐filled anthropometric phantom with a unilateral hip implant. Also the validity of the full MC calculation used as reference method was demonstrated. The dose calculations were performed both in original computed tomography (CT) dataset, which included artifacts, and in corrected CT dataset, where constant Hounsfield unit (HU) value assignment for all the materials was made. In the second phase, a clinical treatment plan was prepared for a prostate cancer patient with a unilateral hip implant. The plan applied a hybrid VMAT technique that included partial arcs that avoided passing through the implant and static beams traversing the implant. Ultimately, the AXB‐calculated dose distribution was compared to the recalculation by the full MC simulation to assess the accuracy of the AXB algorithm in clinical setting. A recalculation with the anisotropic analytical algorithm (AAA) was also performed to quantify the benefit of the improved dose calculation accuracy of type ‘c’ algorithm (AXB) over type ‘b’ algorithm (AAA). The agreement between the AXB algorithm and the full MC model was very good inside and in the vicinity of the implant and elsewhere, which verifies the accuracy of the AXB algorithm for patient plans with beams traversing through high‐Z material, whereas the AAA produced larger discrepancies. PACS numbers: 87.55.‐x, 87.55.D‐, 87.55.K‐, 87.55.kd, 87.55.Qr John Wiley and Sons Inc. 2014-09-08 /pmc/articles/PMC5711096/ /pubmed/25207577 http://dx.doi.org/10.1120/jacmp.v15i5.4912 Text en © 2014 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Ojala, Jarkko
Kapanen, Mika
Sipilä, Petri
Hyödynmaa, Simo
Pitkänen, Maunu
The accuracy of Acuros XB algorithm for radiation beams traversing a metallic hip implant — comparison with measurements and Monte Carlo calculations
title The accuracy of Acuros XB algorithm for radiation beams traversing a metallic hip implant — comparison with measurements and Monte Carlo calculations
title_full The accuracy of Acuros XB algorithm for radiation beams traversing a metallic hip implant — comparison with measurements and Monte Carlo calculations
title_fullStr The accuracy of Acuros XB algorithm for radiation beams traversing a metallic hip implant — comparison with measurements and Monte Carlo calculations
title_full_unstemmed The accuracy of Acuros XB algorithm for radiation beams traversing a metallic hip implant — comparison with measurements and Monte Carlo calculations
title_short The accuracy of Acuros XB algorithm for radiation beams traversing a metallic hip implant — comparison with measurements and Monte Carlo calculations
title_sort accuracy of acuros xb algorithm for radiation beams traversing a metallic hip implant — comparison with measurements and monte carlo calculations
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711096/
https://www.ncbi.nlm.nih.gov/pubmed/25207577
http://dx.doi.org/10.1120/jacmp.v15i5.4912
work_keys_str_mv AT ojalajarkko theaccuracyofacurosxbalgorithmforradiationbeamstraversingametallichipimplantcomparisonwithmeasurementsandmontecarlocalculations
AT kapanenmika theaccuracyofacurosxbalgorithmforradiationbeamstraversingametallichipimplantcomparisonwithmeasurementsandmontecarlocalculations
AT sipilapetri theaccuracyofacurosxbalgorithmforradiationbeamstraversingametallichipimplantcomparisonwithmeasurementsandmontecarlocalculations
AT hyodynmaasimo theaccuracyofacurosxbalgorithmforradiationbeamstraversingametallichipimplantcomparisonwithmeasurementsandmontecarlocalculations
AT pitkanenmaunu theaccuracyofacurosxbalgorithmforradiationbeamstraversingametallichipimplantcomparisonwithmeasurementsandmontecarlocalculations
AT ojalajarkko accuracyofacurosxbalgorithmforradiationbeamstraversingametallichipimplantcomparisonwithmeasurementsandmontecarlocalculations
AT kapanenmika accuracyofacurosxbalgorithmforradiationbeamstraversingametallichipimplantcomparisonwithmeasurementsandmontecarlocalculations
AT sipilapetri accuracyofacurosxbalgorithmforradiationbeamstraversingametallichipimplantcomparisonwithmeasurementsandmontecarlocalculations
AT hyodynmaasimo accuracyofacurosxbalgorithmforradiationbeamstraversingametallichipimplantcomparisonwithmeasurementsandmontecarlocalculations
AT pitkanenmaunu accuracyofacurosxbalgorithmforradiationbeamstraversingametallichipimplantcomparisonwithmeasurementsandmontecarlocalculations