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Dosimetric impact of the 160 MLC on head and neck IMRT treatments

The purpose of this work is to investigate if the change in plan quality with the finer leaf resolution and lower leakage of the 160 MLC would be dosimetrically significant for head and neck intensity‐modulated radiation therapy (IMRT) treatment plans. The 160 MLC consisting of 80 leaves of 0.5 cm o...

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Autores principales: Rassiah‐Szegedi, Prema, Szegedi, Martin, Sarkar, Vikren, Streitmatter, Seth, Huang, Y. Jessica, Zhao, Hui, Salter, Bill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711108/
https://www.ncbi.nlm.nih.gov/pubmed/25493507
http://dx.doi.org/10.1120/jacmp.v15i6.4770
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author Rassiah‐Szegedi, Prema
Szegedi, Martin
Sarkar, Vikren
Streitmatter, Seth
Huang, Y. Jessica
Zhao, Hui
Salter, Bill
author_facet Rassiah‐Szegedi, Prema
Szegedi, Martin
Sarkar, Vikren
Streitmatter, Seth
Huang, Y. Jessica
Zhao, Hui
Salter, Bill
author_sort Rassiah‐Szegedi, Prema
collection PubMed
description The purpose of this work is to investigate if the change in plan quality with the finer leaf resolution and lower leakage of the 160 MLC would be dosimetrically significant for head and neck intensity‐modulated radiation therapy (IMRT) treatment plans. The 160 MLC consisting of 80 leaves of 0.5 cm on each bank, a leaf span of 20 cm, and leakage of less than 0.37% without additional backup jaws was compared against the 120 Millennium MLC with 60 leaves of 0.5 and 1.0 cm, a leaf span of 14.5 cm, and leakage of 2.0%. CT image sets of 16 patients previously treated for stage III and IV head and neck carcinomas were replanned on Prowess 5.0 and Eclipse 11.0 using the 160 MLC and the 120 MLC. IMRT constraints for both sets of 6 MV plans were identical and based on RTOG 0522. Dose‐volume histograms (DVHs), minimum dose, mean dose, maximum dose, and dose to 1 cc to the organ at risks (OAR) and the planning target volume, as recommended by QUANTEC 2010, were compared. Both collimators were able to achieve the target dose to the PTVs. The dose to the organs at risk (brainstem, spinal cord, parotids, and larynx) were 1%–12% (i.e., 0.5–8 Gy for a 70 Gy prescription) lower with the 160 MLC compared to the 120 MLC, depending on the proximity of the organ to the target. The large field HN plans generated with the 160 MLC were dosimetrically advantageous for critical structures, especially those located further away from the central axis, without compromising the target volume. PACS number: 87.55 D‐
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spelling pubmed-57111082018-04-02 Dosimetric impact of the 160 MLC on head and neck IMRT treatments Rassiah‐Szegedi, Prema Szegedi, Martin Sarkar, Vikren Streitmatter, Seth Huang, Y. Jessica Zhao, Hui Salter, Bill J Appl Clin Med Phys Radiation Oncology Physics The purpose of this work is to investigate if the change in plan quality with the finer leaf resolution and lower leakage of the 160 MLC would be dosimetrically significant for head and neck intensity‐modulated radiation therapy (IMRT) treatment plans. The 160 MLC consisting of 80 leaves of 0.5 cm on each bank, a leaf span of 20 cm, and leakage of less than 0.37% without additional backup jaws was compared against the 120 Millennium MLC with 60 leaves of 0.5 and 1.0 cm, a leaf span of 14.5 cm, and leakage of 2.0%. CT image sets of 16 patients previously treated for stage III and IV head and neck carcinomas were replanned on Prowess 5.0 and Eclipse 11.0 using the 160 MLC and the 120 MLC. IMRT constraints for both sets of 6 MV plans were identical and based on RTOG 0522. Dose‐volume histograms (DVHs), minimum dose, mean dose, maximum dose, and dose to 1 cc to the organ at risks (OAR) and the planning target volume, as recommended by QUANTEC 2010, were compared. Both collimators were able to achieve the target dose to the PTVs. The dose to the organs at risk (brainstem, spinal cord, parotids, and larynx) were 1%–12% (i.e., 0.5–8 Gy for a 70 Gy prescription) lower with the 160 MLC compared to the 120 MLC, depending on the proximity of the organ to the target. The large field HN plans generated with the 160 MLC were dosimetrically advantageous for critical structures, especially those located further away from the central axis, without compromising the target volume. PACS number: 87.55 D‐ John Wiley and Sons Inc. 2014-11-08 /pmc/articles/PMC5711108/ /pubmed/25493507 http://dx.doi.org/10.1120/jacmp.v15i6.4770 Text en © 2014 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Rassiah‐Szegedi, Prema
Szegedi, Martin
Sarkar, Vikren
Streitmatter, Seth
Huang, Y. Jessica
Zhao, Hui
Salter, Bill
Dosimetric impact of the 160 MLC on head and neck IMRT treatments
title Dosimetric impact of the 160 MLC on head and neck IMRT treatments
title_full Dosimetric impact of the 160 MLC on head and neck IMRT treatments
title_fullStr Dosimetric impact of the 160 MLC on head and neck IMRT treatments
title_full_unstemmed Dosimetric impact of the 160 MLC on head and neck IMRT treatments
title_short Dosimetric impact of the 160 MLC on head and neck IMRT treatments
title_sort dosimetric impact of the 160 mlc on head and neck imrt treatments
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711108/
https://www.ncbi.nlm.nih.gov/pubmed/25493507
http://dx.doi.org/10.1120/jacmp.v15i6.4770
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