Cargando…

Evaluation of treatment plans using various treatment techniques for the radiotherapy of cutaneous Kaposi's sarcoma developed on the skin of feet

The purpose of this study was to investigate the plan qualities of various treatment modalities for the radiotherapy of cutaneous Kaposi's sarcoma developed on the skin of the foot. A total of six virtual targets were generated on the skin of the foot in CT images. Five types of treatment plans...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Jong Min, Kim, Il Han, Ye, Sung‐Joon, Kim, Kyubo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711114/
https://www.ncbi.nlm.nih.gov/pubmed/25493522
http://dx.doi.org/10.1120/jacmp.v15i6.4970
_version_ 1783283011397091328
author Park, Jong Min
Kim, Il Han
Ye, Sung‐Joon
Kim, Kyubo
author_facet Park, Jong Min
Kim, Il Han
Ye, Sung‐Joon
Kim, Kyubo
author_sort Park, Jong Min
collection PubMed
description The purpose of this study was to investigate the plan qualities of various treatment modalities for the radiotherapy of cutaneous Kaposi's sarcoma developed on the skin of the foot. A total of six virtual targets were generated on the skin of the foot in CT images. Five types of treatment plans were generated using photon beams (PB), electron beams (EB), high‐dose‐rate (HDR) brachytherapy with a Freiburg flap applicator, intensity‐modulated radiation therapy (IMRT), and volumetric‐modulated arc therapy (VMAT) techniques. Plans for each of the six targets (single‐target plans) and also for the combined target consisting of the six single targets combined (multitarget plans) were generated. Dose‐volumetric analysis was performed for the targets and normal tissues. The averaged conformity index (CI) and homogeneity index (HI) values for each single target using PB, EB, HDR, IMRT, and VMAT techniques were 1.97, 2.39, 1.60, 4.60, and 0.80 and 1.05, 1.11, 1.52, 1.04, and 1.04, respectively. For the multitarget, the CI values were 3.99, 5.08, 1.38, 1.95, and 0.84, and the values of HI were 1.10, 1.36, 1.43, 1.06, and 1.04, respectively. The averaged mean doses to normal tissue were 2.5, 2.7, 3.6, 1.7, and 2.9 Gy for single‐target plans, and 21.3, 14.6, 14.2, 14.3, and 13.0 Gy for the multitarget plans, respectively. The VMAT demonstrated dosimetric advantages and better treatment efficiency over other techniques for the radiotherapy of multifocal skin disease of the feet. PACS number: 87.55.dk
format Online
Article
Text
id pubmed-5711114
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-57111142018-04-02 Evaluation of treatment plans using various treatment techniques for the radiotherapy of cutaneous Kaposi's sarcoma developed on the skin of feet Park, Jong Min Kim, Il Han Ye, Sung‐Joon Kim, Kyubo J Appl Clin Med Phys Radiation Oncology Physics The purpose of this study was to investigate the plan qualities of various treatment modalities for the radiotherapy of cutaneous Kaposi's sarcoma developed on the skin of the foot. A total of six virtual targets were generated on the skin of the foot in CT images. Five types of treatment plans were generated using photon beams (PB), electron beams (EB), high‐dose‐rate (HDR) brachytherapy with a Freiburg flap applicator, intensity‐modulated radiation therapy (IMRT), and volumetric‐modulated arc therapy (VMAT) techniques. Plans for each of the six targets (single‐target plans) and also for the combined target consisting of the six single targets combined (multitarget plans) were generated. Dose‐volumetric analysis was performed for the targets and normal tissues. The averaged conformity index (CI) and homogeneity index (HI) values for each single target using PB, EB, HDR, IMRT, and VMAT techniques were 1.97, 2.39, 1.60, 4.60, and 0.80 and 1.05, 1.11, 1.52, 1.04, and 1.04, respectively. For the multitarget, the CI values were 3.99, 5.08, 1.38, 1.95, and 0.84, and the values of HI were 1.10, 1.36, 1.43, 1.06, and 1.04, respectively. The averaged mean doses to normal tissue were 2.5, 2.7, 3.6, 1.7, and 2.9 Gy for single‐target plans, and 21.3, 14.6, 14.2, 14.3, and 13.0 Gy for the multitarget plans, respectively. The VMAT demonstrated dosimetric advantages and better treatment efficiency over other techniques for the radiotherapy of multifocal skin disease of the feet. PACS number: 87.55.dk John Wiley and Sons Inc. 2014-11-08 /pmc/articles/PMC5711114/ /pubmed/25493522 http://dx.doi.org/10.1120/jacmp.v15i6.4970 Text en © 2014 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Park, Jong Min
Kim, Il Han
Ye, Sung‐Joon
Kim, Kyubo
Evaluation of treatment plans using various treatment techniques for the radiotherapy of cutaneous Kaposi's sarcoma developed on the skin of feet
title Evaluation of treatment plans using various treatment techniques for the radiotherapy of cutaneous Kaposi's sarcoma developed on the skin of feet
title_full Evaluation of treatment plans using various treatment techniques for the radiotherapy of cutaneous Kaposi's sarcoma developed on the skin of feet
title_fullStr Evaluation of treatment plans using various treatment techniques for the radiotherapy of cutaneous Kaposi's sarcoma developed on the skin of feet
title_full_unstemmed Evaluation of treatment plans using various treatment techniques for the radiotherapy of cutaneous Kaposi's sarcoma developed on the skin of feet
title_short Evaluation of treatment plans using various treatment techniques for the radiotherapy of cutaneous Kaposi's sarcoma developed on the skin of feet
title_sort evaluation of treatment plans using various treatment techniques for the radiotherapy of cutaneous kaposi's sarcoma developed on the skin of feet
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711114/
https://www.ncbi.nlm.nih.gov/pubmed/25493522
http://dx.doi.org/10.1120/jacmp.v15i6.4970
work_keys_str_mv AT parkjongmin evaluationoftreatmentplansusingvarioustreatmenttechniquesfortheradiotherapyofcutaneouskaposissarcomadevelopedontheskinoffeet
AT kimilhan evaluationoftreatmentplansusingvarioustreatmenttechniquesfortheradiotherapyofcutaneouskaposissarcomadevelopedontheskinoffeet
AT yesungjoon evaluationoftreatmentplansusingvarioustreatmenttechniquesfortheradiotherapyofcutaneouskaposissarcomadevelopedontheskinoffeet
AT kimkyubo evaluationoftreatmentplansusingvarioustreatmenttechniquesfortheradiotherapyofcutaneouskaposissarcomadevelopedontheskinoffeet