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Development of a dose verification system for Vero4DRT using Monte Carlo method

Vero4DRT is an innovative image‐guided radiotherapy system employing a C‐band X‐ray head with gimbal mechanics. The purposes of this study were to propose specific MC models of the linac head and multileaf collimator (MLC) for the Vero4DRT and to verify their accuracy. For a 6 MV photon beam deliver...

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Autores principales: Ishihara, Yoshitomo, Sawada, Akira, Nakamura, Mitsuhiro, Miyabe, Yuki, Tanabe, Hiroaki, Kaneko, Shuji, Takayama, Kenji, Mizowaki, Takashi, Kokubo, Masaki, Hiraoka, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711115/
https://www.ncbi.nlm.nih.gov/pubmed/25493521
http://dx.doi.org/10.1120/jacmp.v15i6.4961
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author Ishihara, Yoshitomo
Sawada, Akira
Nakamura, Mitsuhiro
Miyabe, Yuki
Tanabe, Hiroaki
Kaneko, Shuji
Takayama, Kenji
Mizowaki, Takashi
Kokubo, Masaki
Hiraoka, Masahiro
author_facet Ishihara, Yoshitomo
Sawada, Akira
Nakamura, Mitsuhiro
Miyabe, Yuki
Tanabe, Hiroaki
Kaneko, Shuji
Takayama, Kenji
Mizowaki, Takashi
Kokubo, Masaki
Hiraoka, Masahiro
author_sort Ishihara, Yoshitomo
collection PubMed
description Vero4DRT is an innovative image‐guided radiotherapy system employing a C‐band X‐ray head with gimbal mechanics. The purposes of this study were to propose specific MC models of the linac head and multileaf collimator (MLC) for the Vero4DRT and to verify their accuracy. For a 6 MV photon beam delivered by the Vero4DRT, a simulation code was implemented using EGSnrc. The linac head model and the MLC model were simulated based on its specification. Next, the percent depth dose (PDD) and beam profiles at depths of 15, 100, and 200 mm were simulated under source‐to‐surface distance of 900 and 1000 mm. Field size was set to [Formula: see text] at a depth of 100 mm. Each of the simulated dosimetric metrics was then compared with the corresponding measurements by a 0.125 cc ionization chamber. After that, intra‐ and interleaf leakage, tongue‐and‐groove, and rounded‐leaf profiles were simulated for the static MLC model. Meanwhile, film measurements were performed using EDR2 films under similar conditions to simulation. The measurement for the rounded‐leaf profile was performed using the water phantom and the ionization chamber. The leaf physical density and abutting leaf gap were adjusted to obtain good agreement between the simulated intra‐ and interleaf leakage profiles and measurements. For the MLC model in step‐and‐shoot cases, a pyramid and a prostate IMRT field were simulated, while film measurements were performed using EDR2. For the linac head, exclusive of MLC, the difference in PDD was [Formula: see text] after the buildup region. The simulated beam profiles agreed to within 1.3% at each depth. The MLC model has been shown to reproduce dose measurements within 2.5% for static tests. The MLC is made of tungsten alloy with a purity of 95%. The leaf gap of 0.015 cm and the MLC physical density of [Formula: see text] , which provided the best agreement between the simulated and measured leaf leakage, were assigned to our MC model. As a result, the simulated step‐and‐shoot IMRT dose distributions agreed with the film measurements to within 3.3%, with exception of the penumbra region. We have developed specific MC models of the linac head and the MLC in the Vero4DRT system. The results have demonstrated that our MC models have high accuracy. PACS numbers: 87.55.K‐, 87.56.nk, 87.56.bd
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spelling pubmed-57111152018-04-02 Development of a dose verification system for Vero4DRT using Monte Carlo method Ishihara, Yoshitomo Sawada, Akira Nakamura, Mitsuhiro Miyabe, Yuki Tanabe, Hiroaki Kaneko, Shuji Takayama, Kenji Mizowaki, Takashi Kokubo, Masaki Hiraoka, Masahiro J Appl Clin Med Phys Radiation Oncology Physics Vero4DRT is an innovative image‐guided radiotherapy system employing a C‐band X‐ray head with gimbal mechanics. The purposes of this study were to propose specific MC models of the linac head and multileaf collimator (MLC) for the Vero4DRT and to verify their accuracy. For a 6 MV photon beam delivered by the Vero4DRT, a simulation code was implemented using EGSnrc. The linac head model and the MLC model were simulated based on its specification. Next, the percent depth dose (PDD) and beam profiles at depths of 15, 100, and 200 mm were simulated under source‐to‐surface distance of 900 and 1000 mm. Field size was set to [Formula: see text] at a depth of 100 mm. Each of the simulated dosimetric metrics was then compared with the corresponding measurements by a 0.125 cc ionization chamber. After that, intra‐ and interleaf leakage, tongue‐and‐groove, and rounded‐leaf profiles were simulated for the static MLC model. Meanwhile, film measurements were performed using EDR2 films under similar conditions to simulation. The measurement for the rounded‐leaf profile was performed using the water phantom and the ionization chamber. The leaf physical density and abutting leaf gap were adjusted to obtain good agreement between the simulated intra‐ and interleaf leakage profiles and measurements. For the MLC model in step‐and‐shoot cases, a pyramid and a prostate IMRT field were simulated, while film measurements were performed using EDR2. For the linac head, exclusive of MLC, the difference in PDD was [Formula: see text] after the buildup region. The simulated beam profiles agreed to within 1.3% at each depth. The MLC model has been shown to reproduce dose measurements within 2.5% for static tests. The MLC is made of tungsten alloy with a purity of 95%. The leaf gap of 0.015 cm and the MLC physical density of [Formula: see text] , which provided the best agreement between the simulated and measured leaf leakage, were assigned to our MC model. As a result, the simulated step‐and‐shoot IMRT dose distributions agreed with the film measurements to within 3.3%, with exception of the penumbra region. We have developed specific MC models of the linac head and the MLC in the Vero4DRT system. The results have demonstrated that our MC models have high accuracy. PACS numbers: 87.55.K‐, 87.56.nk, 87.56.bd John Wiley and Sons Inc. 2014-11-08 /pmc/articles/PMC5711115/ /pubmed/25493521 http://dx.doi.org/10.1120/jacmp.v15i6.4961 Text en © 2014 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Ishihara, Yoshitomo
Sawada, Akira
Nakamura, Mitsuhiro
Miyabe, Yuki
Tanabe, Hiroaki
Kaneko, Shuji
Takayama, Kenji
Mizowaki, Takashi
Kokubo, Masaki
Hiraoka, Masahiro
Development of a dose verification system for Vero4DRT using Monte Carlo method
title Development of a dose verification system for Vero4DRT using Monte Carlo method
title_full Development of a dose verification system for Vero4DRT using Monte Carlo method
title_fullStr Development of a dose verification system for Vero4DRT using Monte Carlo method
title_full_unstemmed Development of a dose verification system for Vero4DRT using Monte Carlo method
title_short Development of a dose verification system for Vero4DRT using Monte Carlo method
title_sort development of a dose verification system for vero4drt using monte carlo method
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711115/
https://www.ncbi.nlm.nih.gov/pubmed/25493521
http://dx.doi.org/10.1120/jacmp.v15i6.4961
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