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Inter‐ and intrafractional setup errors and baseline shifts of fiducial markers in patients with liver tumors receiving free‐breathing postoperative radiation analyzed by cone‐beam computed tomography
This study was to evaluate the interfractional and intrafractional setup errors and baseline shifts of golden fiducial markers in patients receiving postoperative radiotherapy (RT) using cone‐beam computed tomography (CBCT) in order to calculate PTV margins for patients with liver cancer. Twelve pat...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711118/ https://www.ncbi.nlm.nih.gov/pubmed/25493517 http://dx.doi.org/10.1120/jacmp.v15i6.4914 |
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author | Zhang, Tao Wang, Weihu Li, Yexiong Jin, Jing Wang, Shulian Song, Yongwen Liu, Yueping |
author_facet | Zhang, Tao Wang, Weihu Li, Yexiong Jin, Jing Wang, Shulian Song, Yongwen Liu, Yueping |
author_sort | Zhang, Tao |
collection | PubMed |
description | This study was to evaluate the interfractional and intrafractional setup errors and baseline shifts of golden fiducial markers in patients receiving postoperative radiotherapy (RT) using cone‐beam computed tomography (CBCT) in order to calculate PTV margins for patients with liver cancer. Twelve patients with liver tumors underwent postoperative RT. CBCT images were acquired before and after the treatment. Off‐line vertebral body match and fiducial marker match were used, respectively. The results of vertebral body match represented the setup errors of the patients, while the results of fiducial marker match represented the absolute position errors of the target volume. Baseline shifts of the target volume were calculated as the absolute target position errors minus setup errors. A total of 12 patients with 214 acquisitions of CBCTs were analyzed. Both Σ and σ of setup errors and baseline shifts in left–right (L/R), superior–inferior (S/I), and anterior–posterior(A/P) directions were calculated, including interfractional and intrafractional uncertainties. Planning target volume (PTV) margins were calculated according to [Formula: see text]. Margins of 1.8 mm, 3.8 mm, and 1.4 mm in L/R, S/I, and A/P directions are needed to compensate intrafractional errors when daily online CBCT correction is used. When CBCT correction with no action level (NAL) protocol is used, PTV margin should be 2.6 mm, 5.9 mm, and 2.6 mm in L/R, S/I, and A/P directions. Margins of 5.5 mm, 14.6 mm, and 7.2 mm were needed to compensate the baseline shifts when electronic portal imaging devices (EPID) or CBCT with bone match is used for online correction of setup error. PACS number: 87.55.‐x |
format | Online Article Text |
id | pubmed-5711118 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-57111182018-04-02 Inter‐ and intrafractional setup errors and baseline shifts of fiducial markers in patients with liver tumors receiving free‐breathing postoperative radiation analyzed by cone‐beam computed tomography Zhang, Tao Wang, Weihu Li, Yexiong Jin, Jing Wang, Shulian Song, Yongwen Liu, Yueping J Appl Clin Med Phys Radiation Oncology Physics This study was to evaluate the interfractional and intrafractional setup errors and baseline shifts of golden fiducial markers in patients receiving postoperative radiotherapy (RT) using cone‐beam computed tomography (CBCT) in order to calculate PTV margins for patients with liver cancer. Twelve patients with liver tumors underwent postoperative RT. CBCT images were acquired before and after the treatment. Off‐line vertebral body match and fiducial marker match were used, respectively. The results of vertebral body match represented the setup errors of the patients, while the results of fiducial marker match represented the absolute position errors of the target volume. Baseline shifts of the target volume were calculated as the absolute target position errors minus setup errors. A total of 12 patients with 214 acquisitions of CBCTs were analyzed. Both Σ and σ of setup errors and baseline shifts in left–right (L/R), superior–inferior (S/I), and anterior–posterior(A/P) directions were calculated, including interfractional and intrafractional uncertainties. Planning target volume (PTV) margins were calculated according to [Formula: see text]. Margins of 1.8 mm, 3.8 mm, and 1.4 mm in L/R, S/I, and A/P directions are needed to compensate intrafractional errors when daily online CBCT correction is used. When CBCT correction with no action level (NAL) protocol is used, PTV margin should be 2.6 mm, 5.9 mm, and 2.6 mm in L/R, S/I, and A/P directions. Margins of 5.5 mm, 14.6 mm, and 7.2 mm were needed to compensate the baseline shifts when electronic portal imaging devices (EPID) or CBCT with bone match is used for online correction of setup error. PACS number: 87.55.‐x John Wiley and Sons Inc. 2014-11-08 /pmc/articles/PMC5711118/ /pubmed/25493517 http://dx.doi.org/10.1120/jacmp.v15i6.4914 Text en © 2014 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Radiation Oncology Physics Zhang, Tao Wang, Weihu Li, Yexiong Jin, Jing Wang, Shulian Song, Yongwen Liu, Yueping Inter‐ and intrafractional setup errors and baseline shifts of fiducial markers in patients with liver tumors receiving free‐breathing postoperative radiation analyzed by cone‐beam computed tomography |
title | Inter‐ and intrafractional setup errors and baseline shifts of fiducial markers in patients with liver tumors receiving free‐breathing postoperative radiation analyzed by cone‐beam computed tomography |
title_full | Inter‐ and intrafractional setup errors and baseline shifts of fiducial markers in patients with liver tumors receiving free‐breathing postoperative radiation analyzed by cone‐beam computed tomography |
title_fullStr | Inter‐ and intrafractional setup errors and baseline shifts of fiducial markers in patients with liver tumors receiving free‐breathing postoperative radiation analyzed by cone‐beam computed tomography |
title_full_unstemmed | Inter‐ and intrafractional setup errors and baseline shifts of fiducial markers in patients with liver tumors receiving free‐breathing postoperative radiation analyzed by cone‐beam computed tomography |
title_short | Inter‐ and intrafractional setup errors and baseline shifts of fiducial markers in patients with liver tumors receiving free‐breathing postoperative radiation analyzed by cone‐beam computed tomography |
title_sort | inter‐ and intrafractional setup errors and baseline shifts of fiducial markers in patients with liver tumors receiving free‐breathing postoperative radiation analyzed by cone‐beam computed tomography |
topic | Radiation Oncology Physics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711118/ https://www.ncbi.nlm.nih.gov/pubmed/25493517 http://dx.doi.org/10.1120/jacmp.v15i6.4914 |
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