Necdin shapes serotonergic development and SERT activity modulating breathing in a mouse model for Prader-Willi syndrome

Prader-Willi syndrome (PWS) is a genetic neurodevelopmental disorder that presents with hypotonia and respiratory distress in neonates. The Necdin-deficient mouse is the only model that reproduces the respiratory phenotype of PWS (central apnea and blunted response to respiratory challenges). Here,...

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Detalles Bibliográficos
Autores principales: Matarazzo, Valéry, Caccialupi, Laura, Schaller, Fabienne, Shvarev, Yuri, Kourdougli, Nazim, Bertoni, Alessandra, Menuet, Clément, Voituron, Nicolas, Deneris, Evan, Gaspar, Patricia, Bezin, Laurent, Durbec, Pascale, Hilaire, Gérard, Muscatelli, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Human Biology and Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711373/
https://www.ncbi.nlm.nih.gov/pubmed/29087295
http://dx.doi.org/10.7554/eLife.32640

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