Phosphatidylinositol 4,5-bisphosphate optical uncaging potentiates exocytosis

Phosphatidylinositol-4,5-bisphosphate [PI(4,5)P(2)] is essential for exocytosis. Classical ways of manipulating PI(4,5)P(2) levels are slower than its metabolism, making it difficult to distinguish effects of PI(4,5)P(2) from those of its metabolites. We developed a membrane-permeant, photoactivatab...

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Detalles Bibliográficos
Autores principales: Walter, Alexander M, Müller, Rainer, Tawfik, Bassam, Wierda, Keimpe DB, Pinheiro, Paulo S, Nadler, André, McCarthy, Anthony W, Ziomkiewicz, Iwona, Kruse, Martin, Reither, Gregor, Rettig, Jens, Lehmann, Martin, Haucke, Volker, Hille, Bertil, Schultz, Carsten, Sørensen, Jakob Balslev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711374/
https://www.ncbi.nlm.nih.gov/pubmed/29068313
http://dx.doi.org/10.7554/eLife.30203

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