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Genetic Disruption of 21-Hydroxylase in Zebrafish Causes Interrenal Hyperplasia

Congenital adrenal hyperplasia is a group of common inherited disorders leading to glucocorticoid deficiency. Most cases are caused by 21-hydroxylase deficiency (21OHD). The systemic consequences of imbalanced steroid hormone biosynthesis due to severe 21OHD remains poorly understood. Therefore, we...

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Detalles Bibliográficos
Autores principales: Eachus, Helen, Zaucker, Andreas, Oakes, James A., Griffin, Aliesha, Weger, Meltem, Güran, Tülay, Taylor, Angela, Harris, Abigail, Greenfield, Andy, Quanson, Jonathan L., Storbeck, Karl-Heinz, Cunliffe, Vincent T., Müller, Ferenc, Krone, Nils
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711382/
https://www.ncbi.nlm.nih.gov/pubmed/28938470
http://dx.doi.org/10.1210/en.2017-00549