Cargando…

Genetic Disruption of 21-Hydroxylase in Zebrafish Causes Interrenal Hyperplasia

Congenital adrenal hyperplasia is a group of common inherited disorders leading to glucocorticoid deficiency. Most cases are caused by 21-hydroxylase deficiency (21OHD). The systemic consequences of imbalanced steroid hormone biosynthesis due to severe 21OHD remains poorly understood. Therefore, we...

Descripción completa

Detalles Bibliográficos
Autores principales:	Eachus, Helen, Zaucker, Andreas, Oakes, James A., Griffin, Aliesha, Weger, Meltem, Güran, Tülay, Taylor, Angela, Harris, Abigail, Greenfield, Andy, Quanson, Jonathan L., Storbeck, Karl-Heinz, Cunliffe, Vincent T., Müller, Ferenc, Krone, Nils
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711382/ https://www.ncbi.nlm.nih.gov/pubmed/28938470 http://dx.doi.org/10.1210/en.2017-00549

Ejemplares similares

Ferredoxin 1b (Fdx1b) Is the Essential Mitochondrial Redox Partner for Cortisol Biosynthesis in Zebrafish
por: Griffin, Aliesha, et al.
Publicado: (2016)

Disrupted-in-Schizophrenia-1 is essential for normal hypothalamic-pituitary-interrenal (HPI) axis function
por: Eachus, Helen, et al.
Publicado: (2017)

Development and Fibronectin Signaling Requirements of the Zebrafish Interrenal Vessel
por: Chiu, Chih-Hao, et al.
Publicado: (2012)

The role of primary cilia in mouse adrenal and zebrafish interrenal development
por: Cogger, K, et al.
Publicado: (2012)

Maternal Cortisol Mediates Hypothalamus-Pituitary-Interrenal Axis Development in Zebrafish
por: Nesan, Dinushan, et al.
Publicado: (2016)

Characterization of the Interrenal Gland and Sexual Traits Development in cyp17a2-Deficient Zebrafish
por: Shi, Shengchi, et al.
Publicado: (2022)

Glucocorticoid deficiency causes transcriptional and post-transcriptional reprogramming of glutamine metabolism
por: Weger, Meltem, et al.
Publicado: (2018)

Bidirectional crosstalk between Hypoxia-Inducible Factor and glucocorticoid signalling in zebrafish larvae
por: Marchi, Davide, et al.
Publicado: (2020)

The anti-platelet drug cilostazol enhances heart rate and interrenal steroidogenesis and exerts a scant effect on innate immune responses in zebrafish
por: Chang, Wei-Chun, et al.
Publicado: (2023)

Crossover of the Hypothalamic Pituitary–Adrenal/Interrenal, –Thyroid, and –Gonadal Axes in Testicular Development
por: Castañeda Cortés, Diana C., et al.
Publicado: (2014)

Glucocorticoid receptor regulates protein chaperone, circadian clock and affective disorder genes in the zebrafish brain
por: Eachus, Helen, et al.
Publicado: (2023)

Phenotype-Based Screening of Synthetic Cannabinoids in a Dravet Syndrome Zebrafish Model
por: Griffin, Aliesha, et al.
Publicado: (2020)

11-Ketotestosterone and 11-Ketodihydrotestosterone in Castration Resistant Prostate Cancer: Potent Androgens Which Can No Longer Be Ignored
por: Pretorius, Elzette, et al.
Publicado: (2016)

A Giant Ovarian Cyst in a Neonate with Classical 21-Hydroxylase Deficiency with Very High Testosterone Levels Demonstrating a High-Dose Hook Effect
por: Güran, Tülay, et al.
Publicado: (2012)

Histopathological evaluation of the interrenal gland (adrenal homolog) of Japanese medaka (Oryzias latipes) exposed to graphene oxide
por: Dasmahapatra, Asok K., et al.
Publicado: (2022)

Treatment and Outcome of Congenital Adrenal Hyperplasia: 21-Hydroxylase Deficiency
por: Lee, Peter A., et al.
Publicado: (2010)

The Complexities in Genotyping of Congenital Adrenal Hyperplasia: 21-Hydroxylase Deficiency
por: Pignatelli, Duarte, et al.
Publicado: (2019)

MondoA regulates gene expression in cholesterol biosynthesis-associated pathways required for zebrafish epiboly
por: Weger, Meltem, et al.
Publicado: (2020)

Persistent Exposure to Environmental Levels of Microcystin-LR Disturbs Cortisol Production via Hypothalamic-Pituitary-Interrenal (HPI) Axis and Subsequently Liver Glucose Metabolism in Adult Male Zebrafish (Danio rerio)
por: Wang, Lingkai, et al.
Publicado: (2020)

notch3 is essential for oligodendrocyte development and vascular integrity in zebrafish
por: Zaucker, Andreas, et al.
Publicado: (2013)

Tools to Image Germplasm Dynamics During Early Zebrafish Development
por: Zaucker, Andreas, et al.
Publicado: (2021)

A Chemical Screening Procedure for Glucocorticoid Signaling with a Zebrafish Larva Luciferase Reporter System
por: Weger, Benjamin D., et al.
Publicado: (2013)

The Effects of Early Life Stress on the Brain and Behaviour: Insights From Zebrafish Models
por: Eachus, Helen, et al.
Publicado: (2021)

Zebrafish as a model to investigate the CRH axis and interactions with DISC1
por: Eachus, Helen, et al.
Publicado: (2022)

Height augmentation in 11β-hydroxylase deficiency congenital adrenal hyperplasia
por: Nour, Munier A, et al.
Publicado: (2015)

Pitfalls in molecular diagnosis of 21-hydroxylase deficiency in congenital adrenal hyperplasia
por: Kolahdouz, Mahsa, et al.
Publicado: (2015)

Gender identity in congenital adrenal hyperplasia secondary to 11-hydroxylase deficiency
por: Bin-Abbas, Bassam S., et al.
Publicado: (2006)

Corrigendum: The Complexities in Genotyping of Congenital Adrenal Hyperplasia: 21-Hydroxylase Deficiency
por: Pignatelli, Duarte, et al.
Publicado: (2020)

11-Oxygenated C19 Steroids Are the Predominant Androgens in Polycystic Ovary Syndrome
por: O’Reilly, Michael W., et al.
Publicado: (2016)

Zebrafish studies identify serotonin receptors mediating antiepileptic activity in Dravet syndrome
por: Griffin, Aliesha L, et al.
Publicado: (2019)

Counter-Regulatory Response to a Fall in Circulating Fatty Acid Levels in Rainbow Trout. Possible Involvement of the Hypothalamus-Pituitary-Interrenal Axis
por: Librán-Pérez, Marta, et al.
Publicado: (2014)

Genotype-Phenotype Correlation in 153 Adult Patients With Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency: Analysis of the United Kingdom Congenital Adrenal Hyperplasia Adult Study Executive (CaHASE) Cohort
por: Krone, Nils, et al.
Publicado: (2013)

Adrenocortical tumor in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency
por: Dung, Vu Chi, et al.
Publicado: (2015)

Phenotype of patients with congenital adrenal hyperplasia due to 11β-hydroxylase deficiency
por: Dung, Vu Chi, et al.
Publicado: (2015)

Birth Size in Neonates with Congenital Adrenal Hyperplasia due to 21-hydroxylase Deficiency
por: Dörr, Helmuth G., et al.
Publicado: (2019)

Sexuality in Males With Congenital Adrenal Hyperplasia Resulting From 21-Hydroxylase Deficiency
por: Gehrmann, Katharina, et al.
Publicado: (2019)

Molecular diagnosis of patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency
por: Espinosa Reyes, Tania Mayvel, et al.
Publicado: (2020)

Quality of Life in Men With Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency
por: Verhees, Myrthe J. M., et al.
Publicado: (2021)

Modified-Release and Conventional Glucocorticoids and Diurnal Androgen Excretion in Congenital Adrenal Hyperplasia
por: Jones, Christopher M., et al.
Publicado: (2016)

Morphometric Evaluation of Interrenal Gland and Kidney Macrophages Aggregates in Normal Healthy Rainbow Trout (Oncorhynchus mykiss) and after Bacterial Challenge with Yersinia ruckeri
por: Gregori, Michela, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_bisff1nd1rgs5t2c73khrt4arq