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The Aspergillus fumigatus farnesyltransferase β-subunit, RamA, mediates growth, virulence, and antifungal susceptibility

Post-translational prenylation mechanisms, including farnesylation and geranylgeranylation, mediate both subcellular localization and protein-protein interaction in eukaryotes. The prenyltransferase complex is an αβ heterodimer in which the essential α-subunit is common to both the farnesyltransfera...

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Detalles Bibliográficos
Autores principales: Norton, Tiffany S., Al Abdallah, Qusai, Hill, Amy M., Lovingood, Rachel V., Fortwendel, Jarrod R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711395/
https://www.ncbi.nlm.nih.gov/pubmed/28489963
http://dx.doi.org/10.1080/21505594.2017.1328343