Cargando…
Endotoxin neutralization by an O-antigen specific monoclonal antibody: A potential novel therapeutic approach against Klebsiella pneumoniae ST258
Klebsiella pneumoniae ST258 is a globally distributed multi-drug resistant pathogen responsible for severe invasive infections. In this study, the different virulence potential of K. pneumoniae ST258 isolates in endotoxin susceptible versus resistant animal models was shown. Furthermore, ST258 clini...
Autores principales: | Szijártó, Valéria, Guachalla, Luis M., Hartl, Katharina, Varga, Cecília, Badarau, Adriana, Mirkina, Irina, Visram, Zehra C., Stulik, Lukas, Power, Christine A., Nagy, Eszter, Nagy, Gábor |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711440/ https://www.ncbi.nlm.nih.gov/pubmed/28103139 http://dx.doi.org/10.1080/21505594.2017.1279778 |
Ejemplares similares
-
Multiple Modes of Action of a Monoclonal Antibody against Multidrug-Resistant Escherichia coli Sequence Type 131-H30
por: Guachalla, Luis M., et al.
Publicado: (2017) -
Disarming Staphylococcus aureus from destroying human cells by simultaneously neutralizing six cytotoxins with two human monoclonal antibodies
por: Rouha, Harald, et al.
Publicado: (2017) -
Preventing lung pathology and mortality in rabbit Staphylococcus aureus pneumonia models with cytotoxin-neutralizing monoclonal IgGs penetrating the epithelial lining fluid
por: Stulik, Lukas, et al.
Publicado: (2019) -
Five birds, one stone: Neutralization of α-hemolysin and 4 bi-component leukocidins of Staphylococcus aureus with a single human monoclonal antibody
por: Rouha, Harald, et al.
Publicado: (2014) -
Discovery of monoclonal antibodies cross-reactive to novel subserotypes of K. pneumoniae O3
por: Guachalla, Luis M., et al.
Publicado: (2017)