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LRSim: A Linked-Reads Simulator Generating Insights for Better Genome Partitioning

Linked-read sequencing, using highly-multiplexed genome partitioning and barcoding, can span hundreds of kilobases to improve de novo assembly, haplotype phasing, and other applications. Based on our analysis of 14 datasets, we introduce LRSim that simulates linked-reads by emulating the library pre...

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Detalles Bibliográficos
Autores principales:	Luo, Ruibang, Sedlazeck, Fritz J., Darby, Charlotte A., Kelly, Stephen M., Schatz, Michael C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Research Network of Computational and Structural Biotechnology 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711661/ https://www.ncbi.nlm.nih.gov/pubmed/29213995 http://dx.doi.org/10.1016/j.csbj.2017.10.002

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