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Human CRMP4 mutation and disrupted Crmp4 expression in mice are associated with ASD characteristics and sexual dimorphism

Autism spectrum disorders (ASD) are more common among boys than girls. The mechanisms responsible for ASD symptoms and their sex differences remain mostly unclear. We previously identified collapsin response mediator protein 4 (CRMP4) as a protein exhibiting sex-different expression during sexual di...

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Detalles Bibliográficos
Autores principales: Tsutiya, Atsuhiro, Nakano, Yui, Hansen-Kiss, Emily, Kelly, Benjamin, Nishihara, Masugi, Goshima, Yoshio, Corsmeier, Don, White, Peter, Herman, Gail E., Ohtani-Kaneko, Ritsuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711804/
https://www.ncbi.nlm.nih.gov/pubmed/29196732
http://dx.doi.org/10.1038/s41598-017-16782-8