Acute Flaccid Paralysis by Enterovirus D68 Infection: First Italian Description in Adult Patient and Role of Electrophysiology

A Peruvian woman was admitted to the Emergency Department, due to an acute flaccid paralysis (AFP) of the upper limbs that progressively involved also lower limbs and respiratory muscles. She previously suffered from non-Hodgkin’s lymphoma and had to undergo hematopoietic stem cell transplantation....

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Autores principales: Ceccanti, Marco, Sbardella, Emilia, Letteri, Federica, De Michele, Manuela, Falcou, Anne, Romanzi, Federica, Onesti, Emanuela, Inghilleri, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711819/
https://www.ncbi.nlm.nih.gov/pubmed/29230194
http://dx.doi.org/10.3389/fneur.2017.00638
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author Ceccanti, Marco
Sbardella, Emilia
Letteri, Federica
De Michele, Manuela
Falcou, Anne
Romanzi, Federica
Onesti, Emanuela
Inghilleri, Maurizio
author_facet Ceccanti, Marco
Sbardella, Emilia
Letteri, Federica
De Michele, Manuela
Falcou, Anne
Romanzi, Federica
Onesti, Emanuela
Inghilleri, Maurizio
author_sort Ceccanti, Marco
collection PubMed
description A Peruvian woman was admitted to the Emergency Department, due to an acute flaccid paralysis (AFP) of the upper limbs that progressively involved also lower limbs and respiratory muscles. She previously suffered from non-Hodgkin’s lymphoma and had to undergo hematopoietic stem cell transplantation. A magnetic resonance imaging showed a T2 hyperintensity in the anterior and central region of the cervical segment with an elective involvement of gray matter. This finding, combined with other clinical, laboratory, and electrophysiological data, led to a diagnosis of AFP. Enterovirus D68 was isolated in the patient’s cerebrospinal fluid, plasma, and throat swab. To our knowledge, this is the first Italian case of AFP by Enterovirus D68 infection in an adult. The diagnostic assessment and management of AFP by Enterovirus D68 are discussed.
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spelling pubmed-57118192017-12-11 Acute Flaccid Paralysis by Enterovirus D68 Infection: First Italian Description in Adult Patient and Role of Electrophysiology Ceccanti, Marco Sbardella, Emilia Letteri, Federica De Michele, Manuela Falcou, Anne Romanzi, Federica Onesti, Emanuela Inghilleri, Maurizio Front Neurol Neuroscience A Peruvian woman was admitted to the Emergency Department, due to an acute flaccid paralysis (AFP) of the upper limbs that progressively involved also lower limbs and respiratory muscles. She previously suffered from non-Hodgkin’s lymphoma and had to undergo hematopoietic stem cell transplantation. A magnetic resonance imaging showed a T2 hyperintensity in the anterior and central region of the cervical segment with an elective involvement of gray matter. This finding, combined with other clinical, laboratory, and electrophysiological data, led to a diagnosis of AFP. Enterovirus D68 was isolated in the patient’s cerebrospinal fluid, plasma, and throat swab. To our knowledge, this is the first Italian case of AFP by Enterovirus D68 infection in an adult. The diagnostic assessment and management of AFP by Enterovirus D68 are discussed. Frontiers Media S.A. 2017-11-27 /pmc/articles/PMC5711819/ /pubmed/29230194 http://dx.doi.org/10.3389/fneur.2017.00638 Text en Copyright © 2017 Ceccanti, Sbardella, Letteri, De Michele, Falcou, Romanzi, Onesti and Inghilleri. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Ceccanti, Marco
Sbardella, Emilia
Letteri, Federica
De Michele, Manuela
Falcou, Anne
Romanzi, Federica
Onesti, Emanuela
Inghilleri, Maurizio
Acute Flaccid Paralysis by Enterovirus D68 Infection: First Italian Description in Adult Patient and Role of Electrophysiology
title Acute Flaccid Paralysis by Enterovirus D68 Infection: First Italian Description in Adult Patient and Role of Electrophysiology
title_full Acute Flaccid Paralysis by Enterovirus D68 Infection: First Italian Description in Adult Patient and Role of Electrophysiology
title_fullStr Acute Flaccid Paralysis by Enterovirus D68 Infection: First Italian Description in Adult Patient and Role of Electrophysiology
title_full_unstemmed Acute Flaccid Paralysis by Enterovirus D68 Infection: First Italian Description in Adult Patient and Role of Electrophysiology
title_short Acute Flaccid Paralysis by Enterovirus D68 Infection: First Italian Description in Adult Patient and Role of Electrophysiology
title_sort acute flaccid paralysis by enterovirus d68 infection: first italian description in adult patient and role of electrophysiology
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711819/
https://www.ncbi.nlm.nih.gov/pubmed/29230194
http://dx.doi.org/10.3389/fneur.2017.00638
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