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Post-transcriptional Regulation of PCSK9 by miR-191, miR-222, and miR-224

Since proprotein convertase subtilisin kexin 9 (PCSK9) discovery, a gene involved in LDL metabolism regulation and cardiovascular diseases (CVD), many therapeutic strategies have been introduced for direct targeting of PCSK9. The main goal of these strategies has been to reduce PCSK9 protein level e...

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Detalles Bibliográficos
Autores principales:	Naeli, Parisa, Mirzadeh Azad, Fatemeh, Malakootian, Mahshid, Seidah, Nabil G., Mowla, Seyed J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711823/ https://www.ncbi.nlm.nih.gov/pubmed/29230236 http://dx.doi.org/10.3389/fgene.2017.00189

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