Resting-state functional MRI reveals altered brain connectivity and its correlation with motor dysfunction in a mouse model of Huntington’s disease

Huntington’s disease (HD) is an autosomal dominant inherited neurodegenerative disorder, and no cure is available currently. Treatment of HD is likely to be most beneficial in the early, possibly pre-manifestation stage. The challenge is to determine the best time for intervention and evaluate putat...

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Detalles Bibliográficos
Autores principales: Li, Qiang, Li, Gang, Wu, Dan, Lu, Hanbing, Hou, Zhipeng, Ross, Christopher A., Yang, Yihong, Zhang, Jiangyang, Duan, Wenzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711837/
https://www.ncbi.nlm.nih.gov/pubmed/29196686
http://dx.doi.org/10.1038/s41598-017-17026-5

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