Cargando…

Small molecule screen in embryonic zebrafish using modular variations to target segmentation

Small molecule in vivo phenotypic screening is used to identify drugs or biological activities by directly assessing effects in intact organisms. However, current screening designs may not exploit the full potential of chemical libraries due to false negatives. Here, we demonstrate a modular small m...

Descripción completa

Detalles Bibliográficos
Autores principales: Richter, Sandra, Schulze, Ulrike, Tomançak, Pavel, Oates, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711842/
https://www.ncbi.nlm.nih.gov/pubmed/29196645
http://dx.doi.org/10.1038/s41467-017-01469-5