Cargando…
A Novel Dopamine Transporter Inhibitor CE-123 Improves Cognitive Flexibility and Maintains Impulsivity in Healthy Male Rats
Reduced cognitive abilities are often characterized by an impairment of flexibility, i.e., the ability to switch from learned rules or categories that were important in certain contexts to different new modalities that rule the task. Drugs targeting the dopamine transporter (DAT) are widely used for...
Autores principales: | Nikiforuk, Agnieszka, Kalaba, Predrag, Ilic, Marija, Korz, Volker, Dragačević, Vladimir, Wackerlig, Judith, Langer, Thierry, Höger, Harald, Golebiowska, Joanna, Popik, Piotr, Lubec, Gert |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711856/ https://www.ncbi.nlm.nih.gov/pubmed/29230168 http://dx.doi.org/10.3389/fnbeh.2017.00222 |
Ejemplares similares
-
Neurophysiological and Neurochemical Effects of the Putative Cognitive Enhancer (S)-CE-123 on Mesocorticolimbic Dopamine System
por: Sagheddu, Claudia, et al.
Publicado: (2020) -
The Novel Atypical Dopamine Uptake Inhibitor (S)-CE-123 Partially Reverses the Effort-Related Effects of the Dopamine Depleting Agent Tetrabenazine and Increases Progressive Ratio Responding
por: Rotolo, Renee A., et al.
Publicado: (2019) -
Novel Dopamine Transporter Inhibitor, CE-123, Ameliorates Spatial Memory Deficits Induced by Maternal Separation in Adolescent Rats: Impact of Sex
por: Grochecki, Pawel, et al.
Publicado: (2022) -
Cognitive profiling and proteomic analysis of the modafinil analogue S-CE-123 in experienced aged rats
por: Gyertyán, István, et al.
Publicado: (2021) -
Low-Affinity/High-Selectivity Dopamine Transport Inhibition Sufficient to Rescue Cognitive Functions in the Aging Rat
por: Lubec, Jana, et al.
Publicado: (2023)