Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity

Light chain amyloidosis (AL), the most common systemic amyloidosis, is caused by the overproduction and the aggregation of monoclonal immunoglobulin light chains (LC) in target organs. Due to genetic rearrangement and somatic hypermutation, virtually, each AL patient presents a different amyloidogen...

Descripción completa

Detalles Bibliográficos
Autores principales: Oberti, Luca, Rognoni, Paola, Barbiroli, Alberto, Lavatelli, Francesca, Russo, Rosaria, Maritan, Martina, Palladini, Giovanni, Bolognesi, Martino, Merlini, Giampaolo, Ricagno, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711917/
https://www.ncbi.nlm.nih.gov/pubmed/29196671
http://dx.doi.org/10.1038/s41598-017-16953-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711917/
https://www.ncbi.nlm.nih.gov/pubmed/29196671
http://dx.doi.org/10.1038/s41598-017-16953-7

Ejemplares similares