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Sequestosome1/p62 protects mouse embryonic fibroblasts against low-dose methylercury-induced cytotoxicity and is involved in clearance of ubiquitinated proteins
Methylmercury (MeHg) is a widely distributed environmental pollutant that causes a series of cytotoxic effects. However, molecular mechanisms underlying MeHg toxicity are not fully understood. Here, we report that sequestosome1/p62 protects mouse embryonic fibroblasts (MEFs) against low-dose MeHg cy...
Autores principales: | Takanezawa, Yasukazu, Nakamura, Ryosuke, Harada, Ryohei, Sone, Yuka, Uraguchi, Shimpei, Kiyono, Masako |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711938/ https://www.ncbi.nlm.nih.gov/pubmed/29196648 http://dx.doi.org/10.1038/s41598-017-17112-8 |
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