A small cassette enables conditional gene inactivation by CRISPR/Cas9

The availability of CRISPR/Cas9 technology has enabled the rapid establishment of gene knockouts in many cell types and even whole organisms. However, conditional inactivation of essential genes remains a challenge. We devised an approach named DECAI (DEgradation based on Cre-regulated- Artificial I...

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Detalles Bibliográficos
Autores principales: Guzzardo, Paloma M., Rashkova, Christina, dos Santos, Rodrigo L., Tehrani, Raha, Collin, Philippe, Bürckstümmer, Tilmann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711947/
https://www.ncbi.nlm.nih.gov/pubmed/29196747
http://dx.doi.org/10.1038/s41598-017-16931-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711947/
https://www.ncbi.nlm.nih.gov/pubmed/29196747
http://dx.doi.org/10.1038/s41598-017-16931-z

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