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BIGH3 Promotes Osteolytic Lesions in Renal Cell Carcinoma Bone Metastasis by Inhibiting Osteoblast Differentiation()()

BACKGROUND: Bone metastasis is common in renal cell carcinoma (RCC), and the lesions are mainly osteolytic. The mechanism of bone destruction in RCC bone metastasis is unknown. METHODS: We used a direct intrafemur injection of mice with bone-derived 786-O RCC cells (Bo-786) as an in vivo model to st...

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Detalles Bibliográficos
Autores principales:	Pan, Tianhong, Lin, Song-Chang, Yu, Kai-Jie, Yu, Guoyu, Song, Jian H., Lewis, Valerae O., Bird, Justin E., Moon, Bryan, Lin, Patrick P., Tannir, Nizar M., Jonasch, Eric, Wood, Christopher G, Gallick, Gary E., Yu-Lee, Li-Yuan, Lin, Sue-Hwa, Satcher, Robert L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2017
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711998/ https://www.ncbi.nlm.nih.gov/pubmed/29190493 http://dx.doi.org/10.1016/j.neo.2017.11.002

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