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Pharmacologic activation of cholinergic alpha7 nicotinic receptors mitigates depressive-like behavior in a mouse model of chronic stress

BACKGROUND: It has been shown that chronic stress-induced depression is associated with exaggerated inflammatory response in the brain. Alpha7 nicotinic acetylcholine receptors (α7nAChRs) regulate the cholinergic anti-inflammatory pathway, but the role of cholinergic signaling and α7nAChR in chronic...

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Detalles Bibliográficos
Autores principales:	Zhao, Dan, Xu, Xulin, Pan, Linna, Zhu, Wei, Fu, Xiaopei, Guo, Lianjun, Lu, Qing, Wang, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712092/ https://www.ncbi.nlm.nih.gov/pubmed/29197398 http://dx.doi.org/10.1186/s12974-017-1007-2

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