Sample size calculations based on a difference in medians for positively skewed outcomes in health care studies

BACKGROUND: In healthcare research, outcomes with skewed probability distributions are common. Sample size calculations for such outcomes are typically based on estimates on a transformed scale (e.g. log) which may sometimes be difficult to obtain. In contrast, estimates of median and variance on th...

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Detalles Bibliográficos
Autores principales: O’Keeffe, Aidan G., Ambler, Gareth, Barber, Julie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712177/
https://www.ncbi.nlm.nih.gov/pubmed/29197347
http://dx.doi.org/10.1186/s12874-017-0426-1

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