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The Enigmatic Role of GBA2 in Controlling Locomotor Function

The non-lysosomal glucosylceramidase GBA2 catalyzes the hydrolysis of glucosylceramide to glucose and ceramide. Loss of GBA2 function results in accumulation of glucosylceramide. Mutations in the human GBA2 gene have been associated with hereditary spastic paraplegia (HSP) and autosomal-recessive ce...

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Detalles Bibliográficos
Autores principales:	Woeste, Marina A., Wachten, Dagmar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712312/ https://www.ncbi.nlm.nih.gov/pubmed/29234271 http://dx.doi.org/10.3389/fnmol.2017.00386

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