Toll-Like Receptor 4 on both Myeloid Cells and Dendritic Cells Is Required for Systemic Inflammation and Organ Damage after Hemorrhagic Shock with Tissue Trauma in Mice

Trauma combined with hemorrhagic shock (HS/T) leads to systemic inflammation, which results in organ injury. Toll-like Receptor 4 (TLR4)-signaling activation contributes to the initiation of inflammatory pathways following HS/T but its cell-specific roles in this setting are not known. We assessed t...

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Detalles Bibliográficos
Autores principales: Zettel, Kent, Korff, Sebastian, Zamora, Ruben, Morelli, Adrian E., Darwiche, Sophie, Loughran, Patricia A., Elson, Greg, Shang, Limin, Salgado-Pires, Susana, Scott, Melanie J., Vodovotz, Yoram, Billiar, Timothy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712321/
https://www.ncbi.nlm.nih.gov/pubmed/29234326
http://dx.doi.org/10.3389/fimmu.2017.01672

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