They Are What You Eat: Can Nutritional Factors during Gestation and Early Infancy Modulate the Neonatal Immune Response?

The ontogeny of the human immune system is sensitive to nutrition even in the very early embryo, with both deficiency and excess of macro- and micronutrients being potentially detrimental. Neonates are particularly vulnerable to infectious disease due to the immaturity of the immune system and modul...

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Detalles Bibliográficos
Autor principal: Prentice, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712338/
https://www.ncbi.nlm.nih.gov/pubmed/29234319
http://dx.doi.org/10.3389/fimmu.2017.01641
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author Prentice, Sarah
author_facet Prentice, Sarah
author_sort Prentice, Sarah
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description The ontogeny of the human immune system is sensitive to nutrition even in the very early embryo, with both deficiency and excess of macro- and micronutrients being potentially detrimental. Neonates are particularly vulnerable to infectious disease due to the immaturity of the immune system and modulation of nutritional immunity may play a role in this sensitivity. This review examines whether nutrition around the time of conception, throughout pregnancy, and in early neonatal life may impact on the developing infant immune system.
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spelling pubmed-57123382017-12-11 They Are What You Eat: Can Nutritional Factors during Gestation and Early Infancy Modulate the Neonatal Immune Response? Prentice, Sarah Front Immunol Immunology The ontogeny of the human immune system is sensitive to nutrition even in the very early embryo, with both deficiency and excess of macro- and micronutrients being potentially detrimental. Neonates are particularly vulnerable to infectious disease due to the immaturity of the immune system and modulation of nutritional immunity may play a role in this sensitivity. This review examines whether nutrition around the time of conception, throughout pregnancy, and in early neonatal life may impact on the developing infant immune system. Frontiers Media S.A. 2017-11-28 /pmc/articles/PMC5712338/ /pubmed/29234319 http://dx.doi.org/10.3389/fimmu.2017.01641 Text en Copyright © 2017 Prentice. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Prentice, Sarah
They Are What You Eat: Can Nutritional Factors during Gestation and Early Infancy Modulate the Neonatal Immune Response?
title They Are What You Eat: Can Nutritional Factors during Gestation and Early Infancy Modulate the Neonatal Immune Response?
title_full They Are What You Eat: Can Nutritional Factors during Gestation and Early Infancy Modulate the Neonatal Immune Response?
title_fullStr They Are What You Eat: Can Nutritional Factors during Gestation and Early Infancy Modulate the Neonatal Immune Response?
title_full_unstemmed They Are What You Eat: Can Nutritional Factors during Gestation and Early Infancy Modulate the Neonatal Immune Response?
title_short They Are What You Eat: Can Nutritional Factors during Gestation and Early Infancy Modulate the Neonatal Immune Response?
title_sort they are what you eat: can nutritional factors during gestation and early infancy modulate the neonatal immune response?
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712338/
https://www.ncbi.nlm.nih.gov/pubmed/29234319
http://dx.doi.org/10.3389/fimmu.2017.01641
work_keys_str_mv AT prenticesarah theyarewhatyoueatcannutritionalfactorsduringgestationandearlyinfancymodulatetheneonatalimmuneresponse

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