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Body Mass Index Influences the Prognostic Impact of Combined Nuclear Insulin Receptor and Estrogen Receptor Expression in Primary Breast Cancer

The prognostic importance of tumor-specific nuclear insulin receptor (InsR) expression in breast cancer is unclear, while membrane and cytoplasmic localization of InsR is better characterized. The insulin signaling network is influenced by obesity and may interact with the estrogen receptor α (ERα)...

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Detalles Bibliográficos
Autores principales:	Björner, Sofie, Rosendahl, Ann H., Simonsson, Maria, Markkula, Andrea, Jirström, Karin, Borgquist, Signe, Rose, Carsten, Ingvar, Christian, Jernström, Helena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712344/ https://www.ncbi.nlm.nih.gov/pubmed/29234306 http://dx.doi.org/10.3389/fendo.2017.00332

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