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Anchoring Vignettes in EQ-5D-5L Questionnaire: Validation of a New Instrument

BACKGROUND: Health Related Quality of Life (HRQoL) is an indicator of patient's physical, psychological and social life. HRQoL is influenced by experience, beliefs, perceptions and expectations, and measures subjective perspective of the patient himself. EQ-5D-5L and SF-12 questionnaires are va...

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Autores principales: Azzolina, Danila, Minto, Clara, Boschetto, Stefania, Martinato, Matteo, Bauce, Barbara, Iliceto, Sabino, Gregori, Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712657/
https://www.ncbi.nlm.nih.gov/pubmed/29238421
http://dx.doi.org/10.2174/1874434601711010144
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author Azzolina, Danila
Minto, Clara
Boschetto, Stefania
Martinato, Matteo
Bauce, Barbara
Iliceto, Sabino
Gregori, Dario
author_facet Azzolina, Danila
Minto, Clara
Boschetto, Stefania
Martinato, Matteo
Bauce, Barbara
Iliceto, Sabino
Gregori, Dario
author_sort Azzolina, Danila
collection PubMed
description BACKGROUND: Health Related Quality of Life (HRQoL) is an indicator of patient's physical, psychological and social life. HRQoL is influenced by experience, beliefs, perceptions and expectations, and measures subjective perspective of the patient himself. EQ-5D-5L and SF-12 questionnaires are validated instruments useful to measure HRQoL, increasingly administered in electronic formats. OBJECTIVE: The main purpose is to evaluate the feasibility of anchoring vignettes for the EQ-5D-5L questionnaire, with the aim to improve intergroup comparability of responses among different subjects. A comparison with SF-12 questionnaire is carried out. METHOD: This is a cross-sectional study conducted at the ambulatories of cardiology of the University Hospital of Padova, in Italy. Thirty-eight subjects with a diagnosis of cardiovascular disease or at risk of cardiovascular disease were enrolled. A factorial analysis has been performed to assess the convergent validity of EQ-5D-5L questionnaire compared to Sf-12. Moreover, a compound Hierarchical Ordered Probit (Chopit) model has been estimated to evaluate if the questionnaire form affects the subjective evaluation process in order to compare EQ-5D-5L with and without vignettes. RESULTS: Correlation and factor analysis demonstrate that EQ_5D questionnaire is coherent with SF-12 in paper format. Chopit model estimation shows that questionnaire format does not affect the subjective question interpretation. Moreover, in a parametric model including vignettes, education attainment, disease severity, and gender are predictors of HRQoL status. CONCLUSION: The EQ-5D including vignettes in electronic format seems to be a valid tool to measure HRQoL as compared to EQ-5D without vignettes in paper format and to SF-12 questionnaire.
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spelling pubmed-57126572017-12-13 Anchoring Vignettes in EQ-5D-5L Questionnaire: Validation of a New Instrument Azzolina, Danila Minto, Clara Boschetto, Stefania Martinato, Matteo Bauce, Barbara Iliceto, Sabino Gregori, Dario Open Nurs J Article BACKGROUND: Health Related Quality of Life (HRQoL) is an indicator of patient's physical, psychological and social life. HRQoL is influenced by experience, beliefs, perceptions and expectations, and measures subjective perspective of the patient himself. EQ-5D-5L and SF-12 questionnaires are validated instruments useful to measure HRQoL, increasingly administered in electronic formats. OBJECTIVE: The main purpose is to evaluate the feasibility of anchoring vignettes for the EQ-5D-5L questionnaire, with the aim to improve intergroup comparability of responses among different subjects. A comparison with SF-12 questionnaire is carried out. METHOD: This is a cross-sectional study conducted at the ambulatories of cardiology of the University Hospital of Padova, in Italy. Thirty-eight subjects with a diagnosis of cardiovascular disease or at risk of cardiovascular disease were enrolled. A factorial analysis has been performed to assess the convergent validity of EQ-5D-5L questionnaire compared to Sf-12. Moreover, a compound Hierarchical Ordered Probit (Chopit) model has been estimated to evaluate if the questionnaire form affects the subjective evaluation process in order to compare EQ-5D-5L with and without vignettes. RESULTS: Correlation and factor analysis demonstrate that EQ_5D questionnaire is coherent with SF-12 in paper format. Chopit model estimation shows that questionnaire format does not affect the subjective question interpretation. Moreover, in a parametric model including vignettes, education attainment, disease severity, and gender are predictors of HRQoL status. CONCLUSION: The EQ-5D including vignettes in electronic format seems to be a valid tool to measure HRQoL as compared to EQ-5D without vignettes in paper format and to SF-12 questionnaire. Bentham Open 2017-10-31 /pmc/articles/PMC5712657/ /pubmed/29238421 http://dx.doi.org/10.2174/1874434601711010144 Text en © 2017 Azzolina et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Article
Azzolina, Danila
Minto, Clara
Boschetto, Stefania
Martinato, Matteo
Bauce, Barbara
Iliceto, Sabino
Gregori, Dario
Anchoring Vignettes in EQ-5D-5L Questionnaire: Validation of a New Instrument
title Anchoring Vignettes in EQ-5D-5L Questionnaire: Validation of a New Instrument
title_full Anchoring Vignettes in EQ-5D-5L Questionnaire: Validation of a New Instrument
title_fullStr Anchoring Vignettes in EQ-5D-5L Questionnaire: Validation of a New Instrument
title_full_unstemmed Anchoring Vignettes in EQ-5D-5L Questionnaire: Validation of a New Instrument
title_short Anchoring Vignettes in EQ-5D-5L Questionnaire: Validation of a New Instrument
title_sort anchoring vignettes in eq-5d-5l questionnaire: validation of a new instrument
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712657/
https://www.ncbi.nlm.nih.gov/pubmed/29238421
http://dx.doi.org/10.2174/1874434601711010144
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