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Thrombospondin-1 Partly Mediates the Cartilage Protective Effect of Adipose-Derived Mesenchymal Stem Cells in Osteoarthritis

OBJECTIVE: Assuming that mesenchymal stem cells (MSCs) respond to the osteoarthritic joint environment to exert a chondroprotective effect, we aimed at investigating the molecular response setup by MSCs after priming by osteoarthritic chondrocytes in cocultures. METHODS: We used primary human osteoa...

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Detalles Bibliográficos
Autores principales:	Maumus, Marie, Manferdini, Cristina, Toupet, Karine, Chuchana, Paul, Casteilla, Louis, Gachet, Mélanie, Jorgensen, Christian, Lisignoli, Gina, Noël, Danièle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712679/ https://www.ncbi.nlm.nih.gov/pubmed/29238343 http://dx.doi.org/10.3389/fimmu.2017.01638

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