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Haplotypes inside the beta-globin gene: use as new biomarkers for beta-thalassemia prenatal diagnosis in north of Iran
BACKGROUND: Beta-thalassemia is common in the Mediterranean area as well as the Middle East and India. Official report in Iran revealed the average prevalence rate of carriers about 4%. More than 20 restriction fragment length polymorphisms (RFLPs) are known in the beta-globin gene cluster and used...
Autores principales: | Hashemi-Soteh, Mohammad Bagher, Mousavi, Seyed Saeed, Tafazoli, Alireza |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713070/ https://www.ncbi.nlm.nih.gov/pubmed/29202846 http://dx.doi.org/10.1186/s12929-017-0396-y |
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