Cargando…

Synergy Effect of Combining Fluorescence and Mid Infrared Fiber Spectroscopy for Kidney Tumor Diagnostics

Matching pairs of tumor and non-tumor kidney tissue samples of four patients were investigated ex vivo using a combination of two methods, attenuated total reflection mid infrared spectroscopy and fluorescence spectroscopy, through respectively prepared and adjusted fiber probes. In order to increas...

Descripción completa

Detalles Bibliográficos
Autores principales: Bogomolov, Andrey, Belikova, Valeria, Zabarylo, Urszula J., Bibikova, Olga, Usenov, Iskander, Sakharova, Tatiana, Krause, Hans, Minet, Olaf, Feliksberger, Elena, Artyushenko, Viacheslav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713099/
https://www.ncbi.nlm.nih.gov/pubmed/29113084
http://dx.doi.org/10.3390/s17112548
_version_ 1783283346783076352
author Bogomolov, Andrey
Belikova, Valeria
Zabarylo, Urszula J.
Bibikova, Olga
Usenov, Iskander
Sakharova, Tatiana
Krause, Hans
Minet, Olaf
Feliksberger, Elena
Artyushenko, Viacheslav
author_facet Bogomolov, Andrey
Belikova, Valeria
Zabarylo, Urszula J.
Bibikova, Olga
Usenov, Iskander
Sakharova, Tatiana
Krause, Hans
Minet, Olaf
Feliksberger, Elena
Artyushenko, Viacheslav
author_sort Bogomolov, Andrey
collection PubMed
description Matching pairs of tumor and non-tumor kidney tissue samples of four patients were investigated ex vivo using a combination of two methods, attenuated total reflection mid infrared spectroscopy and fluorescence spectroscopy, through respectively prepared and adjusted fiber probes. In order to increase the data information content, the measurements on tissue samples in both methods were performed in the same 31 preselected positions. Multivariate data analysis revealed a synergic effect of combining the two methods for the diagnostics of kidney tumor compared to individual techniques.
format Online
Article
Text
id pubmed-5713099
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-57130992017-12-07 Synergy Effect of Combining Fluorescence and Mid Infrared Fiber Spectroscopy for Kidney Tumor Diagnostics Bogomolov, Andrey Belikova, Valeria Zabarylo, Urszula J. Bibikova, Olga Usenov, Iskander Sakharova, Tatiana Krause, Hans Minet, Olaf Feliksberger, Elena Artyushenko, Viacheslav Sensors (Basel) Communication Matching pairs of tumor and non-tumor kidney tissue samples of four patients were investigated ex vivo using a combination of two methods, attenuated total reflection mid infrared spectroscopy and fluorescence spectroscopy, through respectively prepared and adjusted fiber probes. In order to increase the data information content, the measurements on tissue samples in both methods were performed in the same 31 preselected positions. Multivariate data analysis revealed a synergic effect of combining the two methods for the diagnostics of kidney tumor compared to individual techniques. MDPI 2017-11-05 /pmc/articles/PMC5713099/ /pubmed/29113084 http://dx.doi.org/10.3390/s17112548 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Bogomolov, Andrey
Belikova, Valeria
Zabarylo, Urszula J.
Bibikova, Olga
Usenov, Iskander
Sakharova, Tatiana
Krause, Hans
Minet, Olaf
Feliksberger, Elena
Artyushenko, Viacheslav
Synergy Effect of Combining Fluorescence and Mid Infrared Fiber Spectroscopy for Kidney Tumor Diagnostics
title Synergy Effect of Combining Fluorescence and Mid Infrared Fiber Spectroscopy for Kidney Tumor Diagnostics
title_full Synergy Effect of Combining Fluorescence and Mid Infrared Fiber Spectroscopy for Kidney Tumor Diagnostics
title_fullStr Synergy Effect of Combining Fluorescence and Mid Infrared Fiber Spectroscopy for Kidney Tumor Diagnostics
title_full_unstemmed Synergy Effect of Combining Fluorescence and Mid Infrared Fiber Spectroscopy for Kidney Tumor Diagnostics
title_short Synergy Effect of Combining Fluorescence and Mid Infrared Fiber Spectroscopy for Kidney Tumor Diagnostics
title_sort synergy effect of combining fluorescence and mid infrared fiber spectroscopy for kidney tumor diagnostics
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713099/
https://www.ncbi.nlm.nih.gov/pubmed/29113084
http://dx.doi.org/10.3390/s17112548
work_keys_str_mv AT bogomolovandrey synergyeffectofcombiningfluorescenceandmidinfraredfiberspectroscopyforkidneytumordiagnostics
AT belikovavaleria synergyeffectofcombiningfluorescenceandmidinfraredfiberspectroscopyforkidneytumordiagnostics
AT zabarylourszulaj synergyeffectofcombiningfluorescenceandmidinfraredfiberspectroscopyforkidneytumordiagnostics
AT bibikovaolga synergyeffectofcombiningfluorescenceandmidinfraredfiberspectroscopyforkidneytumordiagnostics
AT usenoviskander synergyeffectofcombiningfluorescenceandmidinfraredfiberspectroscopyforkidneytumordiagnostics
AT sakharovatatiana synergyeffectofcombiningfluorescenceandmidinfraredfiberspectroscopyforkidneytumordiagnostics
AT krausehans synergyeffectofcombiningfluorescenceandmidinfraredfiberspectroscopyforkidneytumordiagnostics
AT minetolaf synergyeffectofcombiningfluorescenceandmidinfraredfiberspectroscopyforkidneytumordiagnostics
AT feliksbergerelena synergyeffectofcombiningfluorescenceandmidinfraredfiberspectroscopyforkidneytumordiagnostics
AT artyushenkoviacheslav synergyeffectofcombiningfluorescenceandmidinfraredfiberspectroscopyforkidneytumordiagnostics