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Synergy Effect of Combining Fluorescence and Mid Infrared Fiber Spectroscopy for Kidney Tumor Diagnostics
Matching pairs of tumor and non-tumor kidney tissue samples of four patients were investigated ex vivo using a combination of two methods, attenuated total reflection mid infrared spectroscopy and fluorescence spectroscopy, through respectively prepared and adjusted fiber probes. In order to increas...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713099/ https://www.ncbi.nlm.nih.gov/pubmed/29113084 http://dx.doi.org/10.3390/s17112548 |
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author | Bogomolov, Andrey Belikova, Valeria Zabarylo, Urszula J. Bibikova, Olga Usenov, Iskander Sakharova, Tatiana Krause, Hans Minet, Olaf Feliksberger, Elena Artyushenko, Viacheslav |
author_facet | Bogomolov, Andrey Belikova, Valeria Zabarylo, Urszula J. Bibikova, Olga Usenov, Iskander Sakharova, Tatiana Krause, Hans Minet, Olaf Feliksberger, Elena Artyushenko, Viacheslav |
author_sort | Bogomolov, Andrey |
collection | PubMed |
description | Matching pairs of tumor and non-tumor kidney tissue samples of four patients were investigated ex vivo using a combination of two methods, attenuated total reflection mid infrared spectroscopy and fluorescence spectroscopy, through respectively prepared and adjusted fiber probes. In order to increase the data information content, the measurements on tissue samples in both methods were performed in the same 31 preselected positions. Multivariate data analysis revealed a synergic effect of combining the two methods for the diagnostics of kidney tumor compared to individual techniques. |
format | Online Article Text |
id | pubmed-5713099 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-57130992017-12-07 Synergy Effect of Combining Fluorescence and Mid Infrared Fiber Spectroscopy for Kidney Tumor Diagnostics Bogomolov, Andrey Belikova, Valeria Zabarylo, Urszula J. Bibikova, Olga Usenov, Iskander Sakharova, Tatiana Krause, Hans Minet, Olaf Feliksberger, Elena Artyushenko, Viacheslav Sensors (Basel) Communication Matching pairs of tumor and non-tumor kidney tissue samples of four patients were investigated ex vivo using a combination of two methods, attenuated total reflection mid infrared spectroscopy and fluorescence spectroscopy, through respectively prepared and adjusted fiber probes. In order to increase the data information content, the measurements on tissue samples in both methods were performed in the same 31 preselected positions. Multivariate data analysis revealed a synergic effect of combining the two methods for the diagnostics of kidney tumor compared to individual techniques. MDPI 2017-11-05 /pmc/articles/PMC5713099/ /pubmed/29113084 http://dx.doi.org/10.3390/s17112548 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Communication Bogomolov, Andrey Belikova, Valeria Zabarylo, Urszula J. Bibikova, Olga Usenov, Iskander Sakharova, Tatiana Krause, Hans Minet, Olaf Feliksberger, Elena Artyushenko, Viacheslav Synergy Effect of Combining Fluorescence and Mid Infrared Fiber Spectroscopy for Kidney Tumor Diagnostics |
title | Synergy Effect of Combining Fluorescence and Mid Infrared Fiber Spectroscopy for Kidney Tumor Diagnostics |
title_full | Synergy Effect of Combining Fluorescence and Mid Infrared Fiber Spectroscopy for Kidney Tumor Diagnostics |
title_fullStr | Synergy Effect of Combining Fluorescence and Mid Infrared Fiber Spectroscopy for Kidney Tumor Diagnostics |
title_full_unstemmed | Synergy Effect of Combining Fluorescence and Mid Infrared Fiber Spectroscopy for Kidney Tumor Diagnostics |
title_short | Synergy Effect of Combining Fluorescence and Mid Infrared Fiber Spectroscopy for Kidney Tumor Diagnostics |
title_sort | synergy effect of combining fluorescence and mid infrared fiber spectroscopy for kidney tumor diagnostics |
topic | Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713099/ https://www.ncbi.nlm.nih.gov/pubmed/29113084 http://dx.doi.org/10.3390/s17112548 |
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