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Dosimetric characteristics of electron beams produced by two mobile accelerators, Novac7 and Liac, for intraoperative radiation therapy through Monte Carlo simulation

The Novac7 and Liac are linear accelerators (linacs) dedicated to intraoperative radiation therapy (IORT), which produce high energy, very high dose‐per‐pulse electron beams. The characteristics of the accelerators heads of the Novac7 and Liac are different compared to conventional electron accelera...

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Autores principales: Righi, Sergio, Karaj, Evis, Felici, Giuseppe, Di Martino, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713149/
https://www.ncbi.nlm.nih.gov/pubmed/23318376
http://dx.doi.org/10.1120/jacmp.v14i1.3678
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author Righi, Sergio
Karaj, Evis
Felici, Giuseppe
Di Martino, Fabio
author_facet Righi, Sergio
Karaj, Evis
Felici, Giuseppe
Di Martino, Fabio
author_sort Righi, Sergio
collection PubMed
description The Novac7 and Liac are linear accelerators (linacs) dedicated to intraoperative radiation therapy (IORT), which produce high energy, very high dose‐per‐pulse electron beams. The characteristics of the accelerators heads of the Novac7 and Liac are different compared to conventional electron accelerators. The aim of this work was to investigate the specific characteristics of the Novac7 and Liac electron beams using the Monte Carlo method. The Monte Carlo code BEAMnrc has been employed to model the head and simulate the electron beams. The Monte Carlo simulation was preliminarily validated by comparing the simulated dose distributions with those measured by means of EBT radiochromic film. Then, the energy spectra, mean energy profiles, fluence profiles, photon contamination, and angular distributions were obtained from the Monte Carlo simulation. The Spencer‐Attix water‐to‐air mass restricted collision stopping power ratios ([Formula: see text]) were also calculated. Moreover, the modifications of the percentage depth dose in water (backscatter effect) due to the presence of an attenuator plate composed of a sandwich of a 2 mm aluminum foil and a 4 mm lead foil, commonly used for breast treatments, were evaluated. The calculated [Formula: see text] values are in agreement with those tabulated in the IAEA TRS‐398 dosimetric code of practice within 0.2% and 0.4% at [Formula: see text] (reference depth in water) for the Novac7 and Liac, respectively. These differences are negligible for practical dosimetry. The attenuator plate is sufficient to completely absorb the electron beam for each energy of the Novac7 and Liac; moreover, the shape of the dose distribution in water strongly changes with the introduction of the attenuator plate. This variation depends on the energy of the beam, and it can give rise to an increase in the maximum dose in the range of 3%–9%. PACS number: 87.56.‐v
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spelling pubmed-57131492018-04-02 Dosimetric characteristics of electron beams produced by two mobile accelerators, Novac7 and Liac, for intraoperative radiation therapy through Monte Carlo simulation Righi, Sergio Karaj, Evis Felici, Giuseppe Di Martino, Fabio J Appl Clin Med Phys Radiation Oncology Physics The Novac7 and Liac are linear accelerators (linacs) dedicated to intraoperative radiation therapy (IORT), which produce high energy, very high dose‐per‐pulse electron beams. The characteristics of the accelerators heads of the Novac7 and Liac are different compared to conventional electron accelerators. The aim of this work was to investigate the specific characteristics of the Novac7 and Liac electron beams using the Monte Carlo method. The Monte Carlo code BEAMnrc has been employed to model the head and simulate the electron beams. The Monte Carlo simulation was preliminarily validated by comparing the simulated dose distributions with those measured by means of EBT radiochromic film. Then, the energy spectra, mean energy profiles, fluence profiles, photon contamination, and angular distributions were obtained from the Monte Carlo simulation. The Spencer‐Attix water‐to‐air mass restricted collision stopping power ratios ([Formula: see text]) were also calculated. Moreover, the modifications of the percentage depth dose in water (backscatter effect) due to the presence of an attenuator plate composed of a sandwich of a 2 mm aluminum foil and a 4 mm lead foil, commonly used for breast treatments, were evaluated. The calculated [Formula: see text] values are in agreement with those tabulated in the IAEA TRS‐398 dosimetric code of practice within 0.2% and 0.4% at [Formula: see text] (reference depth in water) for the Novac7 and Liac, respectively. These differences are negligible for practical dosimetry. The attenuator plate is sufficient to completely absorb the electron beam for each energy of the Novac7 and Liac; moreover, the shape of the dose distribution in water strongly changes with the introduction of the attenuator plate. This variation depends on the energy of the beam, and it can give rise to an increase in the maximum dose in the range of 3%–9%. PACS number: 87.56.‐v John Wiley and Sons Inc. 2013-01-07 /pmc/articles/PMC5713149/ /pubmed/23318376 http://dx.doi.org/10.1120/jacmp.v14i1.3678 Text en © 2013 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Righi, Sergio
Karaj, Evis
Felici, Giuseppe
Di Martino, Fabio
Dosimetric characteristics of electron beams produced by two mobile accelerators, Novac7 and Liac, for intraoperative radiation therapy through Monte Carlo simulation
title Dosimetric characteristics of electron beams produced by two mobile accelerators, Novac7 and Liac, for intraoperative radiation therapy through Monte Carlo simulation
title_full Dosimetric characteristics of electron beams produced by two mobile accelerators, Novac7 and Liac, for intraoperative radiation therapy through Monte Carlo simulation
title_fullStr Dosimetric characteristics of electron beams produced by two mobile accelerators, Novac7 and Liac, for intraoperative radiation therapy through Monte Carlo simulation
title_full_unstemmed Dosimetric characteristics of electron beams produced by two mobile accelerators, Novac7 and Liac, for intraoperative radiation therapy through Monte Carlo simulation
title_short Dosimetric characteristics of electron beams produced by two mobile accelerators, Novac7 and Liac, for intraoperative radiation therapy through Monte Carlo simulation
title_sort dosimetric characteristics of electron beams produced by two mobile accelerators, novac7 and liac, for intraoperative radiation therapy through monte carlo simulation
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713149/
https://www.ncbi.nlm.nih.gov/pubmed/23318376
http://dx.doi.org/10.1120/jacmp.v14i1.3678
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