FGF-2b and h-PL Transform Duct and Non-Endocrine Human Pancreatic Cells into Endocrine Insulin Secreting Cells by Modulating Differentiating Genes

Background: Diabetes mellitus (DM) is a multifactorial disease orphan of a cure. Regenerative medicine has been proposed as novel strategy for DM therapy. Human fibroblast growth factor (FGF)-2b controls β-cell clusters via autocrine action, and human placental lactogen (hPL)-A increases functional...

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Detalles Bibliográficos
Autores principales: Donadel, Giulia, Pastore, Donatella, Della-Morte, David, Capuani, Barbara, Lombardo, Marco F., Pacifici, Francesca, Bugliani, Marco, Grieco, Fabio A., Marchetti, Piero, Lauro, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713204/
https://www.ncbi.nlm.nih.gov/pubmed/29068419
http://dx.doi.org/10.3390/ijms18112234

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