Network-Driven Proteogenomics Unveils an Aging-Related Imbalance in the Olfactory IκBα-NFκB p65 Complex Functionality in Tg2576 Alzheimer’s Disease Mouse Model

Olfaction is often deregulated in Alzheimer’s disease (AD) patients, and is also impaired in transgenic Tg2576 AD mice, which overexpress the Swedish mutated form of human amyloid precursor protein (APP). However, little is known about the molecular mechanisms that accompany the neurodegeneration of...

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Detalles Bibliográficos
Autores principales: Palomino-Alonso, Maialen, Lachén-Montes, Mercedes, González-Morales, Andrea, Ausín, Karina, Pérez-Mediavilla, Alberto, Fernández-Irigoyen, Joaquín, Santamaría, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713230/
https://www.ncbi.nlm.nih.gov/pubmed/29077059
http://dx.doi.org/10.3390/ijms18112260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713230/
https://www.ncbi.nlm.nih.gov/pubmed/29077059
http://dx.doi.org/10.3390/ijms18112260

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