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Effect of AICAR and 5-Fluorouracil on X-ray Repair, Cross-Complementing Group 1 Expression, and Consequent Cytotoxicity Regulation in Human HCT-116 Colorectal Cancer Cells

Colorectal cancer (CRC) is one of the leading causes of cancer mortality and 5-Fluorouracil (5-FU) is the most common chemotherapy agent of CRC. A high level of X-ray repair cross complementing group 1 (XRCC1) in cancer cells has been associated with the drug resistance occurrence. Moreover, the act...

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Detalles Bibliográficos
Autores principales:	Lee, Ko-Chao, Lin, Chien-Tsong, Chang, Shun-Fu, Chen, Cheng-Nan, Liu, Jing-Lan, Huang, Wen-Shih
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713332/ https://www.ncbi.nlm.nih.gov/pubmed/29117108 http://dx.doi.org/10.3390/ijms18112363

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