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Glucocorticoids Cause Gender-Dependent Reversal of Hepatic Fibrosis in the MDR2-Knockout Mouse Model
Hepatic cholestasis is associated with a significant suppression of the hypothalamus-pituitary-adrenal axis (HPA). In the present study, we tested the hypothesis that activation of the HPA axis by corticosterone treatment can reverse liver inflammation and fibrosis in a multidrug resistance protein...
Autores principales: | Petrescu, Anca D., Grant, Stephanie, Frampton, Gabriel, Kain, Jessica, Hadidi, Karam, Williams, Elaina, McMillin, Matthew, DeMorrow, Sharon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713358/ https://www.ncbi.nlm.nih.gov/pubmed/29125588 http://dx.doi.org/10.3390/ijms18112389 |
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