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Non-Catalytic Roles of the Topoisomerase IIα C-Terminal Domain
DNA Topoisomerase IIα (Topo IIα) is a ubiquitous enzyme in eukaryotes that performs the strand passage reaction where a double helix of DNA is passed through a second double helix. This unique reaction is critical for numerous cellular processes. However, the enzyme also possesses a C-terminal domai...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713405/ https://www.ncbi.nlm.nih.gov/pubmed/29149026 http://dx.doi.org/10.3390/ijms18112438 |