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Akt1 Stimulates Homologous Recombination Repair of DNA Double-Strand Breaks in a Rad51-Dependent Manner

Akt1 is known to promote non-homologous end-joining (NHEJ)-mediated DNA double-strand break (DSB) repair by stimulation of DNA-PKcs. In the present study, we investigated the effect of Akt1 on homologous recombination (HR)-dependent repair of radiation-induced DSBs in non-small cell lung cancer (NSC...

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Detalles Bibliográficos
Autores principales:	Mueck, Katharina, Rebholz, Simone, Harati, Mozhgan Dehghan, Rodemann, H. Peter, Toulany, Mahmoud
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713439/ https://www.ncbi.nlm.nih.gov/pubmed/29156644 http://dx.doi.org/10.3390/ijms18112473

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