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Proteinase-Activated Receptor 2 May Drive Cancer Progression by Facilitating TGF-β Signaling
The G protein-coupled receptor proteinase-activated receptor 2 (PAR2) has been implicated in various aspects of cellular physiology including inflammation, obesity and cancer. In cancer, it usually acts as a driver of cancer progression in various tumor types by promoting invasion and metastasis in...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713460/ https://www.ncbi.nlm.nih.gov/pubmed/29165389 http://dx.doi.org/10.3390/ijms18112494 |