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IgG1 Is Required for Optimal Protection after Immunization with the Purified Porin OmpD from Salmonella Typhimurium

In mice, the IgG subclass induced after Ag encounter can reflect the nature of the Ag. Th2 Ags such as alum-precipitated proteins and helminths induce IgG1, whereas Th1 Ags, such as Salmonella Typhimurium, predominantly induce IgG2a. The contribution of different IgG isotypes to protection against b...

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Detalles Bibliográficos
Autores principales:	Zhang, Yang, Dominguez-Medina, Coral, Cumley, Nicola J., Heath, Jennifer N., Essex, Sarah J., Bobat, Saeeda, Schager, Anna, Goodall, Margaret, Kracker, Sven, Buckley, Christopher D., May, Robin C., Kingsley, Robert A., MacLennan, Calman A., López-Macías, Constantino, Cunningham, Adam F., Toellner, Kai-Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAI 2017
Materias:	Immunotherapy and Vaccines
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713499/ https://www.ncbi.nlm.nih.gov/pubmed/29127147 http://dx.doi.org/10.4049/jimmunol.1700952

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