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Development of coated liposomes loaded with ghrelin for nose-to-brain delivery for the treatment of cachexia

The aim of the present study was to develop a ghrelin-containing formulation based on liposomes coated with chitosan intended for nose–brain delivery for the treatment of cachexia. Among the three types of liposomes developed, anionic liposomes provided the best results in terms of encapsulation eff...

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Detalles Bibliográficos
Autores principales: Salade, Laurent, Wauthoz, Nathalie, Deleu, Magali, Vermeersch, Marjorie, De Vriese, Carine, Amighi, Karim, Goole, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713684/
https://www.ncbi.nlm.nih.gov/pubmed/29238190
http://dx.doi.org/10.2147/IJN.S147650