A novel transdermal nanoethosomal gel of betahistine dihydrochloride for weight gain control: in-vitro and in-vivo characterization

BACKGROUND: Betahistine dihydrochloride (BDH) is a histamine analog used to control weight gain, with short elimination half-life and gastric irritation as side effects. OBJECTIVE: The aim of the current investigation is to formulate and optimize a topical BDH ethosomal gel for weight gain control....

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Detalles Bibliográficos
Autores principales: El-Menshawe, Shahira F, Ali, Adel Ahmed, Halawa, Abdelkhalk Ali, Srag El-Din, Ahmed SG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713695/
https://www.ncbi.nlm.nih.gov/pubmed/29238164
http://dx.doi.org/10.2147/DDDT.S144652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713695/
https://www.ncbi.nlm.nih.gov/pubmed/29238164
http://dx.doi.org/10.2147/DDDT.S144652

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