AAV-CRISPR/Cas9–Mediated Depletion of VEGFR2 Blocks Angiogenesis In Vitro

PURPOSE: Pathologic angiogenesis is a component of many diseases, including neovascular age-related macular degeneration, proliferation diabetic retinopathy, as well as tumor growth and metastasis. The purpose of this project was to examine whether the system of adeno-associated viral (AAV)–mediated...

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Detalles Bibliográficos
Autores principales: Wu, Wenyi, Duan, Yajian, Ma, Gaoen, Zhou, Guohong, Park-Windhol, Cindy, D'Amore, Patricia A., Lei, Hetian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Biochemistry and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714046/
https://www.ncbi.nlm.nih.gov/pubmed/29204648
http://dx.doi.org/10.1167/iovs.17-21902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714046/
https://www.ncbi.nlm.nih.gov/pubmed/29204648
http://dx.doi.org/10.1167/iovs.17-21902

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