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AAV-CRISPR/Cas9–Mediated Depletion of VEGFR2 Blocks Angiogenesis In Vitro
PURPOSE: Pathologic angiogenesis is a component of many diseases, including neovascular age-related macular degeneration, proliferation diabetic retinopathy, as well as tumor growth and metastasis. The purpose of this project was to examine whether the system of adeno-associated viral (AAV)–mediated...
Autores principales: | Wu, Wenyi, Duan, Yajian, Ma, Gaoen, Zhou, Guohong, Park-Windhol, Cindy, D'Amore, Patricia A., Lei, Hetian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714046/ https://www.ncbi.nlm.nih.gov/pubmed/29204648 http://dx.doi.org/10.1167/iovs.17-21902 |
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