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Cooperative RecA clustering: the key to efficient homology searching

The mechanism by which pre-synaptic RecA nucleoprotein filaments efficiently locate sequence homology across genomic DNA remains unclear. Here, using atomic force microscopy, we directly investigate the intermediates of the RecA-mediated homologous recombination process and find it to be highly coop...

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Detalles Bibliográficos
Autores principales:	Lee, Andrew J., Sharma, Rajan, Hobbs, Jamie K., Wälti, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714135/ https://www.ncbi.nlm.nih.gov/pubmed/28977583 http://dx.doi.org/10.1093/nar/gkx769

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