A group II metabotropic glutamate receptor 3 (mGlu3, GRM3) isoform implicated in schizophrenia interacts with canonical mGlu3 and reduces ligand binding

As well as being expressed as a full-length transcript, the group II metabotropic glutamate receptor 3 (GRM3, mGlu3) gene is expressed as an mRNA isoform which lacks exon 4 (GRM3Δ4) and which is predicted to encode a protein with a novel C terminus (called mGlu3Δ4). This variant may contribute to th...

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Detalles Bibliográficos
Autores principales: García-Bea, Aintzane, Bermudez, Isabel, Harrison, Paul J, Lane, Tracy A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714154/
https://www.ncbi.nlm.nih.gov/pubmed/28655286
http://dx.doi.org/10.1177/0269881117715597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714154/
https://www.ncbi.nlm.nih.gov/pubmed/28655286
http://dx.doi.org/10.1177/0269881117715597

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