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Is ascorbate Dr Jekyll or Mr Hyde in the Cu(Aβ) mediated oxidative stress linked to Alzheimer’s disease?†

Evaluation of the pro versus antioxidant activity of ascorbate regarding Cu(Aβ) induced reactive oxygen species production in the context of Alzheimer’s disease shows that a protective activity can only be observed at high ascorbate concentration for exogenous molecules but not for the amyloid-β pep...

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Detalles Bibliográficos
Autores principales: Cheignon, Clémence, Collin, Fabrice, Faller, Peter, Hureau, Christelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714186/
https://www.ncbi.nlm.nih.gov/pubmed/27264439
http://dx.doi.org/10.1039/c6dt01979j