Competition between translation initiation factor eIF5 and its mimic protein 5MP determines non-AUG initiation rate genome-wide

In the human genome, translation initiation from non-AUG codons plays an important role in various gene regulation programs. However, mechanisms regulating the non-AUG initiation rate remain poorly understood. Here, we show that the non-AUG initiation rate is nearly consistent under a fixed nucleoti...

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Detalles Bibliográficos
Autores principales: Tang, Leiming, Morris, Jacob, Wan, Ji, Moore, Chelsea, Fujita, Yoshihiko, Gillaspie, Sarah, Aube, Eric, Nanda, Jagpreet, Marques, Maud, Jangal, Maika, Anderson, Abbey, Cox, Christian, Hiraishi, Hiroyuki, Dong, Leiming, Saito, Hirohide, Singh, Chingakham Ranjit, Witcher, Michael, Topisirovic, Ivan, Qian, Shu-Bing, Asano, Katsura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714202/
https://www.ncbi.nlm.nih.gov/pubmed/28981728
http://dx.doi.org/10.1093/nar/gkx808

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