Cargando…
Structural insights into RNA unwinding and degradation by RNase R
RNase R is a conserved exoribonuclease in the RNase II family that primarily participates in RNA decay in all kingdoms of life. RNase R degrades duplex RNA with a 3′ overhang, suggesting that it has RNA unwinding activity in addition to its 3′-to-5′ exoribonuclease activity. However, how RNase R coo...
Autores principales: | Chu, Lee-Ya, Hsieh, Tung-Ju, Golzarroshan, Bagher, Chen, Yi-Ping, Agrawal, Sashank, Yuan, Hanna S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714204/ https://www.ncbi.nlm.nih.gov/pubmed/29036353 http://dx.doi.org/10.1093/nar/gkx880 |
Ejemplares similares
-
Crystal structure of dimeric human PNPase reveals why disease-linked mutants suffer from low RNA import and degradation activities
por: Golzarroshan, Bagher, et al.
Publicado: (2018) -
Dimeric assembly of human Suv3 helicase promotes its RNA unwinding function in mitochondrial RNA degradosome for RNA decay
por: Jain, Monika, et al.
Publicado: (2022) -
RNA recognition motifs of disease-linked RNA-binding proteins contribute to amyloid formation
por: Agrawal, Sashank, et al.
Publicado: (2019) -
Molecular mechanism of RNase R substrate sensitivity for RNA ribose methylation
por: Abula, Abudureyimu, et al.
Publicado: (2021) -
Revealing transient structures of nucleosomes as DNA unwinds
por: Chen, Yujie, et al.
Publicado: (2014)