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Structural insights into RNA unwinding and degradation by RNase R

RNase R is a conserved exoribonuclease in the RNase II family that primarily participates in RNA decay in all kingdoms of life. RNase R degrades duplex RNA with a 3′ overhang, suggesting that it has RNA unwinding activity in addition to its 3′-to-5′ exoribonuclease activity. However, how RNase R coo...

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Detalles Bibliográficos
Autores principales: Chu, Lee-Ya, Hsieh, Tung-Ju, Golzarroshan, Bagher, Chen, Yi-Ping, Agrawal, Sashank, Yuan, Hanna S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714204/
https://www.ncbi.nlm.nih.gov/pubmed/29036353
http://dx.doi.org/10.1093/nar/gkx880

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